Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones

K. C. Nicolaou, Kenji Namoto, Jim Li, Andreas Ritzén, Trond Ulven, Mitsuru Shoji, Dan Zaharevitz, Rick Gussio, Dan L. Sackett, Rita D. Ward, Anne Hensler, Tito Fojo, Paraskevi Giannakakou

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)
Original languageEnglish
Pages (from-to)69-75
Number of pages7
JournalChemBioChem
Volume2
Issue number1
DOIs
Publication statusPublished - 2001
Externally publishedYes

Keywords

  • Antitumor agents
  • Epothilones
  • Natural products
  • Structure-activity relationships
  • Synthesis design

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Organic Chemistry

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