Synthesis and nematocidal activity of diarylnonanoids related to malabaricones

Shinzo Hosoi; Fumiyuki Kiuchi; Norio Nakamura; Masaaki Imasho; Mohammad Ahad Ali; Youhei Sasaki; Eriko Tanaka; Yoshiyuki Tsumamoto; Kaoru Kondo; Yoshisuke Tsuda

doi:10.1248/cpb.47.37

Synthesis and nematocidal activity of diarylnonanoids related to malabaricones

Shinzo Hosoi, Fumiyuki Kiuchi, Norio Nakamura, Masaaki Imasho, Mohammad Ahad Ali, Youhei Sasaki, Eriko Tanaka, Yoshiyuki Tsumamoto, Kaoru Kondo, Yoshisuke Tsuda

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Twenty diarylnonanones were synthesized and their nematocidal activity was examined. Among those, the p-hydroxy compound 16 exhibited the strongest activity comparable to the natural diarylnonanoids, malabaricones A and C. Diarylundecanoid 57 also showed appreciable activity.

Original language	English
Pages (from-to)	37-43
Number of pages	7
Journal	Chemical and Pharmaceutical Bulletin
Volume	47
Issue number	1
DOIs	https://doi.org/10.1248/cpb.47.37
Publication status	Published - 1999 Jan
Externally published	Yes

Keywords

Diarylnonanoid
Diarylundecanoid
Malabaricone
Nematocidal activity
Structure-activity relationship
Toxocara canis

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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abstract = "Twenty diarylnonanones were synthesized and their nematocidal activity was examined. Among those, the p-hydroxy compound 16 exhibited the strongest activity comparable to the natural diarylnonanoids, malabaricones A and C. Diarylundecanoid 57 also showed appreciable activity.",

keywords = "Diarylnonanoid, Diarylundecanoid, Malabaricone, Nematocidal activity, Structure-activity relationship, Toxocara canis",

author = "Shinzo Hosoi and Fumiyuki Kiuchi and Norio Nakamura and Masaaki Imasho and Ali, {Mohammad Ahad} and Youhei Sasaki and Eriko Tanaka and Yoshiyuki Tsumamoto and Kaoru Kondo and Yoshisuke Tsuda",

year = "1999",

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doi = "10.1248/cpb.47.37",

language = "English",

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T1 - Synthesis and nematocidal activity of diarylnonanoids related to malabaricones

AU - Hosoi, Shinzo

AU - Kiuchi, Fumiyuki

AU - Nakamura, Norio

AU - Imasho, Masaaki

AU - Ali, Mohammad Ahad

AU - Sasaki, Youhei

AU - Tanaka, Eriko

AU - Tsumamoto, Yoshiyuki

AU - Kondo, Kaoru

AU - Tsuda, Yoshisuke

PY - 1999/1

Y1 - 1999/1

N2 - Twenty diarylnonanones were synthesized and their nematocidal activity was examined. Among those, the p-hydroxy compound 16 exhibited the strongest activity comparable to the natural diarylnonanoids, malabaricones A and C. Diarylundecanoid 57 also showed appreciable activity.

AB - Twenty diarylnonanones were synthesized and their nematocidal activity was examined. Among those, the p-hydroxy compound 16 exhibited the strongest activity comparable to the natural diarylnonanoids, malabaricones A and C. Diarylundecanoid 57 also showed appreciable activity.

KW - Diarylnonanoid

KW - Diarylundecanoid

KW - Malabaricone

KW - Nematocidal activity

KW - Structure-activity relationship

KW - Toxocara canis

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JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 1

ER -

Synthesis and nematocidal activity of diarylnonanoids related to malabaricones

Abstract

Keywords

ASJC Scopus subject areas

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