Synthesis of a photocontrollable hydrogen sulfide donor using ketoprofenate photocages

Naoki Fukushima; Naoya Ieda; Kiyoshi Sasakura; Tetsuo Nagano; Kenjiro Hanaoka; Takayoshi Suzuki; Naoki Miyata; Hidehiko Nakagawa

doi:10.1039/c3cc47421f

Synthesis of a photocontrollable hydrogen sulfide donor using ketoprofenate photocages

Naoki Fukushima
, Naoya Ieda
, Kiyoshi Sasakura
, Tetsuo Nagano
, Kenjiro Hanaoka
, Takayoshi Suzuki
, Naoki Miyata
, Hidehiko Nakagawa

Research output: Contribution to journal › Article › peer-review

86 Citations (Scopus)

Abstract

We report the design, synthesis and application of a directly photocontrollable hydrogen sulfide (H₂S) donor, which releases H₂S proportionally to the intensity and duration of photoirradiation. Photocontrolled H₂S release from this donor was also demonstrated in bovine serum. This H₂S donor should be suitable for use in various biological systems.

Original language	English
Pages (from-to)	587-589
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	5
DOIs	https://doi.org/10.1039/c3cc47421f
Publication status	Published - 2014 Dec 10
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c3cc47421f

Cite this

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abstract = "We report the design, synthesis and application of a directly photocontrollable hydrogen sulfide (H2S) donor, which releases H2S proportionally to the intensity and duration of photoirradiation. Photocontrolled H2S release from this donor was also demonstrated in bovine serum. This H2S donor should be suitable for use in various biological systems.",

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AU - Fukushima, Naoki

AU - Ieda, Naoya

AU - Sasakura, Kiyoshi

AU - Nagano, Tetsuo

AU - Hanaoka, Kenjiro

AU - Suzuki, Takayoshi

AU - Miyata, Naoki

AU - Nakagawa, Hidehiko

PY - 2014/12/10

Y1 - 2014/12/10

N2 - We report the design, synthesis and application of a directly photocontrollable hydrogen sulfide (H2S) donor, which releases H2S proportionally to the intensity and duration of photoirradiation. Photocontrolled H2S release from this donor was also demonstrated in bovine serum. This H2S donor should be suitable for use in various biological systems.

AB - We report the design, synthesis and application of a directly photocontrollable hydrogen sulfide (H2S) donor, which releases H2S proportionally to the intensity and duration of photoirradiation. Photocontrolled H2S release from this donor was also demonstrated in bovine serum. This H2S donor should be suitable for use in various biological systems.

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Synthesis of a photocontrollable hydrogen sulfide donor using ketoprofenate photocages

Abstract

ASJC Scopus subject areas

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