Abstract
Syntheses of natural products and their derivatives require compounds of ever-increasing complexity. Therefore, the control of selectivity becomes more challenging under conventional kinetic and thermodynamic conditions in solution. Dynamic crystallization (alternatively referred to as crystallization-induced transformation: CIT) has been recognized as a practical approach to control the selectivity when the desired product is a less-soluble crystal under equilibrium conditions. This highlight review summarizes the applications of dynamic crystallization to natural product synthesis.
| Original language | English |
|---|---|
| Article number | upae244 |
| Journal | Chemistry Letters |
| Volume | 54 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2025 Jan 1 |
Keywords
- crystallization-induced transformation
- dynamic crystallization
- total synthesis
ASJC Scopus subject areas
- General Chemistry