Synthesis of new peptidic glycoclusters derived from β-alanine

Koji Sato, Noriyasu Hada, Tadahiro Takeda

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


The synthesis of an asymmetric glycocluster 1 has been achieved by coupling of a sugar unit with the β-alanine polypeptide, the principal chain, and combining a carbohydrate chain with the side chain causing it to branch from the N terminal. The synthesis of this side chain multivalent ligands is based on the scaffolding of some ω-amino acid (glycine, β-alanine, and GABA) derivatives. This method facilitated the synthesis of the cluster, of which the length of each unit differs.

Original languageEnglish
Pages (from-to)9331-9335
Number of pages5
JournalTetrahedron Letters
Issue number52
Publication statusPublished - 2003 Dec 22
Externally publishedYes


  • Carbohydrate- protein interaction
  • D-galactose
  • Glycocluster
  • Unit synthesis
  • β-peptide

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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