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Synthesis of various water-soluble C60 derivatives and their superoxide-quenching activity

  • Kensuke Okuda
  • , Takashi Hirota
  • , Masaaki Hirobe
  • , Tetsuo Nagano
  • , Masataka Mochizuki
  • , Tadahiko Mashino

Research output: Contribution to journal › Article › peer-review

Abstract

In order to examine the utility of fullerene as a medicinal application, we evaluated the reaction between fullerene derivatives and active oxygen species in vitro. This paper describes the synthesis of various water-soluble C60 derivatives (cationic and anionic) and evaluation of their superoxide (O2-) quenching activity. Cationic C60 derivatives showed fairly high efficiency.

Original languageEnglish
Pages (from-to)89-104
Number of pages16
JournalFullerene Science and Technology
Volume8
Issue number1
DOIs
Publication statusPublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • General Chemical Engineering

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