Synthetic studies of zoanthamine/norzoanthamine alkaloids: Advanced intermediate for the heterocyclic aminal core

Naotsuka Hikage; Hironori Furukawa; Ken ichi Takao; Susumu Kobayashi

doi:10.1016/S0040-4039(98)01284-2

Synthetic studies of zoanthamine/norzoanthamine alkaloids: Advanced intermediate for the heterocyclic aminal core

Naotsuka Hikage, Hironori Furukawa, Ken ichi Takao, Susumu Kobayashi

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

An advanced intermediate for the heterocyclic aminal core of zoanthamine/norzoanthamine alkaloids was prepared in an enantio and stereoselective manner. Contiguous quaternary chiral centers were selectively constructed utilizing a stereoselective cuprate addition to the readily available (+)-Wieland-Miescher ketone.

Original language	English
Pages (from-to)	6237-6240
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	34
DOIs	https://doi.org/10.1016/S0040-4039(98)01284-2
Publication status	Published - 1998 Aug 20
Externally published	Yes

Keywords

Alkaloids;animals;amino;ketones;marine metabolites

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(98)01284-2

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abstract = "An advanced intermediate for the heterocyclic aminal core of zoanthamine/norzoanthamine alkaloids was prepared in an enantio and stereoselective manner. Contiguous quaternary chiral centers were selectively constructed utilizing a stereoselective cuprate addition to the readily available (+)-Wieland-Miescher ketone.",

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author = "Naotsuka Hikage and Hironori Furukawa and Takao, {Ken ichi} and Susumu Kobayashi",

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AU - Takao, Ken ichi

AU - Kobayashi, Susumu

PY - 1998/8/20

Y1 - 1998/8/20

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AB - An advanced intermediate for the heterocyclic aminal core of zoanthamine/norzoanthamine alkaloids was prepared in an enantio and stereoselective manner. Contiguous quaternary chiral centers were selectively constructed utilizing a stereoselective cuprate addition to the readily available (+)-Wieland-Miescher ketone.

KW - Alkaloids;animals;amino;ketones;marine metabolites

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ER -

Synthetic studies of zoanthamine/norzoanthamine alkaloids: Advanced intermediate for the heterocyclic aminal core

Abstract

Keywords

ASJC Scopus subject areas

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