Synthetic studies on altohyrtins (spongistatins): Synthesis of the C15- C28 (CD) spiroacetal portion

Takeshi Terauchi; Taro Terauchi; Ippei Sato; Tomoharu Tsukada; Naoki Kanoh; Masaya Nakata

doi:10.1016/S0040-4039(00)00237-9

Synthetic studies on altohyrtins (spongistatins): Synthesis of the C15- C28 (CD) spiroacetal portion

Takeshi Terauchi, Taro Terauchi, Ippei Sato, Tomoharu Tsukada, Naoki Kanoh, Masaya Nakata

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

The C15-C28 portion of altohyrtins (spongistatins) was prepared in a convergent manner from methyl (S)-3-hydroxy-2-methylpropionate, D-arabitol, and diacetone-D-glucose via dithiane couplings with epoxides as the key segment coupling process.

Original language	English
Pages (from-to)	2649-2653
Number of pages	5
Journal	Tetrahedron Letters
Volume	41
Issue number	15
DOIs	https://doi.org/10.1016/S0040-4039(00)00237-9
Publication status	Published - 2000 Apr 8
Externally published	Yes

Keywords

Altohyrtins
Dithianes
Epoxides
Spiro compounds

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)00237-9

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title = "Synthetic studies on altohyrtins (spongistatins): Synthesis of the C15- C28 (CD) spiroacetal portion",

abstract = "The C15-C28 portion of altohyrtins (spongistatins) was prepared in a convergent manner from methyl (S)-3-hydroxy-2-methylpropionate, D-arabitol, and diacetone-D-glucose via dithiane couplings with epoxides as the key segment coupling process.",

keywords = "Altohyrtins, Dithianes, Epoxides, Spiro compounds",

author = "Takeshi Terauchi and Taro Terauchi and Ippei Sato and Tomoharu Tsukada and Naoki Kanoh and Masaya Nakata",

note = "Funding Information: Financial support by Takeda Science Foundation is gratefully acknowledged.",

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doi = "10.1016/S0040-4039(00)00237-9",

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T1 - Synthetic studies on altohyrtins (spongistatins)

T2 - Synthesis of the C15- C28 (CD) spiroacetal portion

AU - Terauchi, Takeshi

AU - Terauchi, Taro

AU - Sato, Ippei

AU - Tsukada, Tomoharu

AU - Kanoh, Naoki

AU - Nakata, Masaya

N1 - Funding Information: Financial support by Takeda Science Foundation is gratefully acknowledged.

PY - 2000/4/8

Y1 - 2000/4/8

N2 - The C15-C28 portion of altohyrtins (spongistatins) was prepared in a convergent manner from methyl (S)-3-hydroxy-2-methylpropionate, D-arabitol, and diacetone-D-glucose via dithiane couplings with epoxides as the key segment coupling process.

AB - The C15-C28 portion of altohyrtins (spongistatins) was prepared in a convergent manner from methyl (S)-3-hydroxy-2-methylpropionate, D-arabitol, and diacetone-D-glucose via dithiane couplings with epoxides as the key segment coupling process.

KW - Altohyrtins

KW - Dithianes

KW - Epoxides

KW - Spiro compounds

UR - http://www.scopus.com/inward/record.url?scp=0034620922&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034620922&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)00237-9

DO - 10.1016/S0040-4039(00)00237-9

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SN - 0040-4039

VL - 41

SP - 2649

EP - 2653

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 15

ER -

Synthetic studies on altohyrtins (spongistatins): Synthesis of the C15- C28 (CD) spiroacetal portion

Abstract

Keywords

ASJC Scopus subject areas

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