Synthetic studies on novel fucosylated glycosphingolipids from the millipede, Parafontaria laminata armigera

Noriyasu Hada; Isao Ohtsuka; Mutsumi Sugita; Tadahiro Takeda

doi:10.1016/S0040-4039(00)01603-8

Synthetic studies on novel fucosylated glycosphingolipids from the millipede, Parafontaria laminata armigera

Noriyasu Hada, Isao Ohtsuka, Mutsumi Sugita, Tadahiro Takeda

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

A novel glycosphingolipid, β-D-Manp-(1→4)-[(α-L-Fucp-(1→3)]-β-D-Glcp-(1→1)-Cer, from the millipede, Parafontaria laminata armigera, was synthesized. A key reaction of this synthetic procedure is the formation of a spiro-orthoester and its reduction for β-selective mannosylation. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	9065-9068
Number of pages	4
Journal	Tetrahedron Letters
Volume	41
Issue number	47
DOIs	https://doi.org/10.1016/S0040-4039(00)01603-8
Publication status	Published - 2000 Nov 18
Externally published	Yes

Keywords

Chemical synthesis
Glycosphingolipids
Parafontaria laminata armigera

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/S0040-4039(00)01603-8

Cite this

@article{45d06d7557f341c1a5be444bb5120992,

title = "Synthetic studies on novel fucosylated glycosphingolipids from the millipede, Parafontaria laminata armigera",

abstract = "A novel glycosphingolipid, β-D-Manp-(1→4)-[(α-L-Fucp-(1→3)]-β-D-Glcp-(1→1)-Cer, from the millipede, Parafontaria laminata armigera, was synthesized. A key reaction of this synthetic procedure is the formation of a spiro-orthoester and its reduction for β-selective mannosylation. (C) 2000 Elsevier Science Ltd.",

keywords = "Chemical synthesis, Glycosphingolipids, Parafontaria laminata armigera",

author = "Noriyasu Hada and Isao Ohtsuka and Mutsumi Sugita and Tadahiro Takeda",

note = "Funding Information: This work was supported by the Uehara Memorial Foundation and also supported by a Grant-in-Aid for Encouragement of Young Scientists, No. 70296531, from the Ministry of Education, Science, Sports and Culture of Japan. The authors thank Dr. H. Ohtake (Faculty of Pharmaceutical Sciences, Teikyo University) for valuable discussions.",

year = "2000",

month = nov,

day = "18",

doi = "10.1016/S0040-4039(00)01603-8",

language = "English",

volume = "41",

pages = "9065--9068",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "47",

}

TY - JOUR

T1 - Synthetic studies on novel fucosylated glycosphingolipids from the millipede, Parafontaria laminata armigera

AU - Hada, Noriyasu

AU - Ohtsuka, Isao

AU - Sugita, Mutsumi

AU - Takeda, Tadahiro

N1 - Funding Information: This work was supported by the Uehara Memorial Foundation and also supported by a Grant-in-Aid for Encouragement of Young Scientists, No. 70296531, from the Ministry of Education, Science, Sports and Culture of Japan. The authors thank Dr. H. Ohtake (Faculty of Pharmaceutical Sciences, Teikyo University) for valuable discussions.

PY - 2000/11/18

Y1 - 2000/11/18

N2 - A novel glycosphingolipid, β-D-Manp-(1→4)-[(α-L-Fucp-(1→3)]-β-D-Glcp-(1→1)-Cer, from the millipede, Parafontaria laminata armigera, was synthesized. A key reaction of this synthetic procedure is the formation of a spiro-orthoester and its reduction for β-selective mannosylation. (C) 2000 Elsevier Science Ltd.

AB - A novel glycosphingolipid, β-D-Manp-(1→4)-[(α-L-Fucp-(1→3)]-β-D-Glcp-(1→1)-Cer, from the millipede, Parafontaria laminata armigera, was synthesized. A key reaction of this synthetic procedure is the formation of a spiro-orthoester and its reduction for β-selective mannosylation. (C) 2000 Elsevier Science Ltd.

KW - Chemical synthesis

KW - Glycosphingolipids

KW - Parafontaria laminata armigera

UR - http://www.scopus.com/inward/record.url?scp=0034684532&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034684532&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)01603-8

DO - 10.1016/S0040-4039(00)01603-8

M3 - Article

AN - SCOPUS:0034684532

SN - 0040-4039

VL - 41

SP - 9065

EP - 9068

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 47

ER -

Synthetic studies on novel fucosylated glycosphingolipids from the millipede, Parafontaria laminata armigera

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this