Target-selective degradation of cancer-related proteins by novel photosensitizers for molecular-targeted photodynamic therapy

Kazunobu Toshima; Shuho Tanimoto; Kana Tsumura; Kazuo Umezawa; Daisuke Takahashi

doi:10.1111/j.1349-7006.2009.01226.x

Target-selective degradation of cancer-related proteins by novel photosensitizers for molecular-targeted photodynamic therapy

Kazunobu Toshima, Shuho Tanimoto, Kana Tsumura, Kazuo Umezawa, Daisuke Takahashi

Department of Applied Chemistry

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Proteins are key players in many biological events including cancers. The development of novel photosensitizers for the selective degradation of cancer-related proteins has attracted much attention in the fields of photodynamic therapy for various cancers. In this review article, several novel photosensitizers, which selectively degrade cancer-related proteins under photoirradiation and mild conditions without any further additives, are introduced. This novel class of photosensitizers promises bright prospects for finding molecular-targeted drugs for cancer photodynamic therapy in the near future.

Original language	English
Pages (from-to)	1581-1584
Number of pages	4
Journal	Cancer science
Volume	100
Issue number	9
DOIs	https://doi.org/10.1111/j.1349-7006.2009.01226.x
Publication status	Published - 2009 Sept

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1349-7006.2009.01226.x

Cite this

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abstract = "Proteins are key players in many biological events including cancers. The development of novel photosensitizers for the selective degradation of cancer-related proteins has attracted much attention in the fields of photodynamic therapy for various cancers. In this review article, several novel photosensitizers, which selectively degrade cancer-related proteins under photoirradiation and mild conditions without any further additives, are introduced. This novel class of photosensitizers promises bright prospects for finding molecular-targeted drugs for cancer photodynamic therapy in the near future.",

author = "Kazunobu Toshima and Shuho Tanimoto and Kana Tsumura and Kazuo Umezawa and Daisuke Takahashi",

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AU - Toshima, Kazunobu

AU - Tanimoto, Shuho

AU - Tsumura, Kana

AU - Umezawa, Kazuo

AU - Takahashi, Daisuke

PY - 2009/9

Y1 - 2009/9

N2 - Proteins are key players in many biological events including cancers. The development of novel photosensitizers for the selective degradation of cancer-related proteins has attracted much attention in the fields of photodynamic therapy for various cancers. In this review article, several novel photosensitizers, which selectively degrade cancer-related proteins under photoirradiation and mild conditions without any further additives, are introduced. This novel class of photosensitizers promises bright prospects for finding molecular-targeted drugs for cancer photodynamic therapy in the near future.

AB - Proteins are key players in many biological events including cancers. The development of novel photosensitizers for the selective degradation of cancer-related proteins has attracted much attention in the fields of photodynamic therapy for various cancers. In this review article, several novel photosensitizers, which selectively degrade cancer-related proteins under photoirradiation and mild conditions without any further additives, are introduced. This novel class of photosensitizers promises bright prospects for finding molecular-targeted drugs for cancer photodynamic therapy in the near future.

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Target-selective degradation of cancer-related proteins by novel photosensitizers for molecular-targeted photodynamic therapy

Abstract

ASJC Scopus subject areas

UN SDGs

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