Tau Phosphorylation—Much More than a Biomarker

Sumihiro Maeda; Lennart Mucke

doi:10.1016/j.neuron.2016.10.011

Tau Phosphorylation—Much More than a Biomarker

Sumihiro Maeda, Lennart Mucke

Research output: Contribution to journal › Short survey › peer-review

9 Citations (Scopus)

Abstract

Lasagna-Reeves et al. (2016) demonstrate that preventing the kinase Nuak1 from phosphorylating the microtubule-associated protein tau reduces the level of potentially pathogenic tau species in brain, a novel therapeutic strategy that could help counteract Alzheimer's disease and several other neurological disorders.

Original language	English
Pages (from-to)	265-267
Number of pages	3
Journal	Neuron
Volume	92
Issue number	2
DOIs	https://doi.org/10.1016/j.neuron.2016.10.011
Publication status	Published - 2016 Oct 19
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/j.neuron.2016.10.011

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title = "Tau Phosphorylation—Much More than a Biomarker",

abstract = "Lasagna-Reeves et al. (2016) demonstrate that preventing the kinase Nuak1 from phosphorylating the microtubule-associated protein tau reduces the level of potentially pathogenic tau species in brain, a novel therapeutic strategy that could help counteract Alzheimer's disease and several other neurological disorders.",

author = "Sumihiro Maeda and Lennart Mucke",

note = "Funding Information: L.M. and S.M. are supported by the Tau Consortium. L.M. is a co-inventor on tau-related patents owned by the Gladstone Institutes. L.M. is also the principal investigator of sponsored research collaborations of the Gladstone Institutes with Bristol-Myers Squibb and with Cure Network Dolby Acceleration Partners. Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

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T1 - Tau Phosphorylation—Much More than a Biomarker

AU - Maeda, Sumihiro

AU - Mucke, Lennart

N1 - Funding Information: L.M. and S.M. are supported by the Tau Consortium. L.M. is a co-inventor on tau-related patents owned by the Gladstone Institutes. L.M. is also the principal investigator of sponsored research collaborations of the Gladstone Institutes with Bristol-Myers Squibb and with Cure Network Dolby Acceleration Partners. Publisher Copyright: © 2016 Elsevier Inc.

PY - 2016/10/19

Y1 - 2016/10/19

N2 - Lasagna-Reeves et al. (2016) demonstrate that preventing the kinase Nuak1 from phosphorylating the microtubule-associated protein tau reduces the level of potentially pathogenic tau species in brain, a novel therapeutic strategy that could help counteract Alzheimer's disease and several other neurological disorders.

AB - Lasagna-Reeves et al. (2016) demonstrate that preventing the kinase Nuak1 from phosphorylating the microtubule-associated protein tau reduces the level of potentially pathogenic tau species in brain, a novel therapeutic strategy that could help counteract Alzheimer's disease and several other neurological disorders.

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DO - 10.1016/j.neuron.2016.10.011

M3 - Short survey

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AN - SCOPUS:84992363280

SN - 0896-6273

VL - 92

SP - 265

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JO - Neuron

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IS - 2

ER -

Tau Phosphorylation—Much More than a Biomarker

Abstract

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