Tear film overview

M. Uchino, K. Tsubota

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


The major functions of the tear film are to: (1) maintain a smooth surface for light refraction, (2) lubricate the eyelids, (3) supply the cornea with nutrients by transporting oxygen and a limited number of other nutrients to the avascular cornea, (4) provide white blood cells with access to the cornea and conjunctiva, (5) remove foreign materials from the cornea and conjunctiva, (6) defend the ocular surface from the pathogens via specific and nonspecific antibacterial substances, and (7) protect the ocular surface from free-radical insults with antioxidants such as ascorbic acid, lactoferrin, uric acid, and cysteine.

Original languageEnglish
Title of host publicationEncyclopedia of the Eye, Four-Volume Set
Number of pages6
ISBN (Electronic)9780123742032
ISBN (Print)9780123741981
Publication statusPublished - 2010 Jan 1


  • Dry eye
  • Lipids
  • Mucins
  • Proteins
  • Tear-film function
  • Tear-film structure

ASJC Scopus subject areas

  • Medicine(all)


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