Relações lacrimejantes: Estresse oxidativo, inflamação e doenças oculares

Translated title of the contribution: Tearful relations: Oxidative stress, inflammation and eye diseases

Tais Hitomi Wakamatsu, Murat Dogru, Kazuo Tsubota

Research output: Contribution to journalArticlepeer-review

121 Citations (Scopus)


Oxidative stress is caused by an imbalance between the production of reactive oxygen species and ability the biological systems' defense mechanisms necessary to eliminate the stress. It has been accepted that oxidative stress is involved in many acute and chronic diseases and even in normal aging. Recently, increased awareness of oxidative stress damage and its relation with ocular surface diseases incite researchers to discover possible mechanisms in the development of dry eye disease. This review focuses on the evaluation of the influence of oxidative stress on eye diseases emphasizing its relation with the pathogenesis of dry eye disease.

Translated title of the contributionTearful relations: Oxidative stress, inflammation and eye diseases
Original languagePortuguese
Pages (from-to)72-79
Number of pages8
JournalArquivos Brasileiros de Oftalmologia
Issue number6 SUPP
Publication statusPublished - 2009
Externally publishedYes


  • Dry eye syndromes
  • Eye diseases
  • Oxidative stress
  • Tears/enzymology

ASJC Scopus subject areas

  • Ophthalmology


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