Telomerase assay for diagnosis of esophageal cancer

K. Koyanagi, S. Ozawa, N. Ando, Y. Kitagawa, M. Ueda, M. Kitajima

Research output: Contribution to journalReview articlepeer-review

Abstract

Esophageal squamous cell carcinoma is one of the aggressive diseases that has poor outcome. Therefore it is appeared that early diagnosis is very important for improving its outcome. Iodine staining method is useful for detecting the abnormal squamous epithelium and unstaining lesions by iodine contain the early esophageal cancers. Recently, telomerase activity that provides an immortal capacity for the cells has been measured in many tissues. We measured the telomerase activity in the samples of unstaining lesion by iodine using a polymerase chain reaction-based assay and described the relation between telomerase activity and histopathological findings.

Original languageEnglish
Pages (from-to)1171-1175
Number of pages5
JournalNippon rinsho. Japanese journal of clinical medicine
Volume56
Issue number5
Publication statusPublished - 1998 May

ASJC Scopus subject areas

  • Medicine(all)

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