Tetrahydroswertianolin (1), a new tetrahydroxanthone glycoside, was isolated from the whole plant of Swertia japonica MAKINO (Gentianaceae). Its structure was determined by chemical and spectroscopic methods including 2D- NMR. This compound was found to be very effective in immunologically induced liver injury in mice.
- D- galactosamine/lipopolysaccharide-induced liver injury
- Swertia japonica
ASJC Scopus subject areas
- Drug Discovery