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The anti-oxidative role of ABCG2 in corneal epithelial cells
Miyuki Kubota
, Shigeto Shimmura
, Hideyuki Miyashita
, Motoko Kawashima
, Tetsuya Kawakita
, Kazuo Tsubota
Research output
:
Contribution to journal
›
Article
›
peer-review
24
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Citations (Scopus)
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Keyphrases
Antioxidant Activity
100%
Corneal Endothelium
100%
ATP Binding Cassette Subfamily G Member 2 (ABCG2)
100%
Mitoxantrone
36%
Knock-in Mouse Model
27%
Hypoxia
27%
Side Population Cells
18%
Corneal Epithelial
18%
Epithelial Cell Line
18%
Progenitor Cells
9%
Quantitative PCR
9%
High Concentration
9%
IC50
9%
Epithelial Progenitors
9%
Corneal Epithelium
9%
Epithelial Cells
9%
Cell Death
9%
Cytotoxicity Assay
9%
Hoechst 33342
9%
Flow Cytometry
9%
Homeostasis
9%
Oxidative Stress
9%
Stress-induced
9%
Oxidative Damage
9%
Cell-based
9%
Efflux
9%
Pro-oxidant
9%
Propidium Iodide Staining
9%
Epithelial Phenotype
9%
Control Cell
9%
Ko143
9%
Reserpine
9%
ABCG2 Inhibitor
9%
Death Ratio
9%
Dose-dependent
9%
Type Control
9%
Knockout Cell Lines
9%
Pharmacology, Toxicology and Pharmaceutical Science
ABCG2
100%
Antioxidant
100%
Mitoxantrone
57%
Hypoxia
42%
Knockout Mouse
42%
IC50
14%
Hoe 33342
14%
Flow Cytometry
14%
Oxidizing Agent
14%
Effusion
14%
Propidium Iodide
14%
1,2,3,4,6,7,12,12a Octahydro 6 Isobutyl 9 Methoxy 1,4 dioxopyrazino[1',2':1,6]pyrido[3,4 B]indole 3 Propanoic Acid Tert Butyl Ester
14%
Reserpine
14%
Cytotoxicity Assay
14%
Low Drug Dose
14%