The basic and clinical studies on cefsulodin in pediatric field

Hironobu Akita; Satoshi Iwata; Yukio Iwasaki; Takefumi Kanemitsu; Haruki Hattori; Keiji Jozaki; Masahiro Hotta; Naoya Yamashita; Seiichiro Nanri; Keisuke Sunagawa; Takashi Iwata; Mitsuru Osano; Yasuo Ichihashi

doi:10.11553/antibiotics1968b.35.2652

The basic and clinical studies on cefsulodin in pediatric field

Hironobu Akita, Satoshi Iwata, Yukio Iwasaki, Takefumi Kanemitsu, Haruki Hattori, Keiji Jozaki, Masahiro Hotta, Naoya Yamashita, Seiichiro Nanri, Keisuke Sunagawa, Takashi Iwata, Mitsuru Osano, Yasuo Ichihashi

Research output: Contribution to journal › Article › peer-review

Abstract

A new cephalosporin cefsulodin (CFS) was studied basically and clinically and the following results were obtained. 1. The serum levels of 25 mg/kg of CFS administered intravenously were 39.5 mcg/ml after 30 minutes, 22.6mcg/ml after1hour, 11.6 mcg/ml after 2 hours, 6.0 mcg/ml after 4 hours and 2.1 mcg/ml after 6 hours. The half life from serum was 84 minutes. 2. Clinical response on 4 cases of Pseudomonas aeruginosa infections were all good. 3. The slight elevations of GOT,GPT were observed by the drug administrations in1case. From the above results, CFS was effective drug to P. aeruginosa infections by intravenous administration of 25 mg/kg of CFS.

Original language	English
Pages (from-to)	2652-2656
Number of pages	5
Journal	the japanese journal of antibiotics
Volume	35
Issue number	11
DOIs	https://doi.org/10.11553/antibiotics1968b.35.2652
Publication status	Published - 1982
Externally published	Yes

ASJC Scopus subject areas

Microbiology (medical)
Pharmacology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.11553/antibiotics1968b.35.2652

Cite this

@article{c9dc6637d1c74332be7d683bca60f08e,

title = "The basic and clinical studies on cefsulodin in pediatric field",

abstract = "A new cephalosporin cefsulodin (CFS) was studied basically and clinically and the following results were obtained. 1. The serum levels of 25 mg/kg of CFS administered intravenously were 39.5 mcg/ml after 30 minutes, 22.6mcg/ml after1hour, 11.6 mcg/ml after 2 hours, 6.0 mcg/ml after 4 hours and 2.1 mcg/ml after 6 hours. The half life from serum was 84 minutes. 2. Clinical response on 4 cases of Pseudomonas aeruginosa infections were all good. 3. The slight elevations of GOT,GPT were observed by the drug administrations in1case. From the above results, CFS was effective drug to P. aeruginosa infections by intravenous administration of 25 mg/kg of CFS.",

author = "Hironobu Akita and Satoshi Iwata and Yukio Iwasaki and Takefumi Kanemitsu and Haruki Hattori and Keiji Jozaki and Masahiro Hotta and Naoya Yamashita and Seiichiro Nanri and Keisuke Sunagawa and Takashi Iwata and Mitsuru Osano and Yasuo Ichihashi",

year = "1982",

doi = "10.11553/antibiotics1968b.35.2652",

language = "English",

volume = "35",

pages = "2652--2656",

journal = "the japanese journal of antibiotics",

issn = "0368-2781",

publisher = "Japan Antibiotics Research Association",

number = "11",

}

TY - JOUR

T1 - The basic and clinical studies on cefsulodin in pediatric field

AU - Akita, Hironobu

AU - Iwata, Satoshi

AU - Iwasaki, Yukio

AU - Kanemitsu, Takefumi

AU - Hattori, Haruki

AU - Jozaki, Keiji

AU - Hotta, Masahiro

AU - Yamashita, Naoya

AU - Nanri, Seiichiro

AU - Sunagawa, Keisuke

AU - Iwata, Takashi

AU - Osano, Mitsuru

AU - Ichihashi, Yasuo

PY - 1982

Y1 - 1982

N2 - A new cephalosporin cefsulodin (CFS) was studied basically and clinically and the following results were obtained. 1. The serum levels of 25 mg/kg of CFS administered intravenously were 39.5 mcg/ml after 30 minutes, 22.6mcg/ml after1hour, 11.6 mcg/ml after 2 hours, 6.0 mcg/ml after 4 hours and 2.1 mcg/ml after 6 hours. The half life from serum was 84 minutes. 2. Clinical response on 4 cases of Pseudomonas aeruginosa infections were all good. 3. The slight elevations of GOT,GPT were observed by the drug administrations in1case. From the above results, CFS was effective drug to P. aeruginosa infections by intravenous administration of 25 mg/kg of CFS.

AB - A new cephalosporin cefsulodin (CFS) was studied basically and clinically and the following results were obtained. 1. The serum levels of 25 mg/kg of CFS administered intravenously were 39.5 mcg/ml after 30 minutes, 22.6mcg/ml after1hour, 11.6 mcg/ml after 2 hours, 6.0 mcg/ml after 4 hours and 2.1 mcg/ml after 6 hours. The half life from serum was 84 minutes. 2. Clinical response on 4 cases of Pseudomonas aeruginosa infections were all good. 3. The slight elevations of GOT,GPT were observed by the drug administrations in1case. From the above results, CFS was effective drug to P. aeruginosa infections by intravenous administration of 25 mg/kg of CFS.

UR - http://www.scopus.com/inward/record.url?scp=0020213001&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020213001&partnerID=8YFLogxK

U2 - 10.11553/antibiotics1968b.35.2652

DO - 10.11553/antibiotics1968b.35.2652

M3 - Article

C2 - 7169665

AN - SCOPUS:0020213001

SN - 0368-2781

VL - 35

SP - 2652

EP - 2656

JO - the japanese journal of antibiotics

JF - the japanese journal of antibiotics

IS - 11

ER -

The basic and clinical studies on cefsulodin in pediatric field

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this