The center of sadness, pain, and recognition

Richi Niida, Masaru Mimura

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)


The posterior cingulate cortex (Brodmann area, BA 23) is the hub of the default mode network (DMN). Moreover, its network connectivity decreases early in Alzheimer disease. The anterior cingulate cortex (BA 24) is connected to networks such as the DMN, working memory network (WMN), and salience network (SN) and plays a role in network coordination. The subgenual anterior cingulate cortex (sgACC) on the rostral region of the anterior cingulated cortex is suggested to be associated with depression.

Original languageEnglish
Pages (from-to)417-426
Number of pages10
JournalBrain and Nerve
Issue number4
Publication statusPublished - 2017 Apr 1


  • Alzheimer disease
  • Anterior cingulate cortex
  • Default mode network
  • Depression
  • Posterior cingulate cortex

ASJC Scopus subject areas

  • Clinical Neurology


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