The Cerebral Arterial Wall in the Development and Growth of Intracranial Aneurysms

Pasquale Marco Abbate; A. T.M. Hasibul Hasan; Alice Venier; Vincent Vauclin; Silvia Pizzuto; Alessandro Sgreccia; Federico Di Maria; Oguzhan Coskun; Katsuhiro Mizutani; Georges Rodesch; Arturo Consoli

doi:10.3390/app12125964

The Cerebral Arterial Wall in the Development and Growth of Intracranial Aneurysms

Pasquale Marco Abbate, A. T.M. Hasibul Hasan, Alice Venier, Vincent Vauclin, Silvia Pizzuto, Alessandro Sgreccia, Federico Di Maria, Oguzhan Coskun, Katsuhiro Mizutani, Georges Rodesch, Arturo Consoli

Department of Neurosurgery

Research output: Contribution to journal › Review article › peer-review

Abstract

A considerable number of people harbor intracranial aneurysms (IA), which is a focal or segmental disease of the arterial wall. The pathophysiologic mechanisms of IAs formation, growth, and rupture are complex. The mechanism also differs with respect to the type of aneurysm. In broad aspects, aneurysms may be considered a disease of the vessel wall. In addition to the classic risk factors and the genetic/environmental conditions, altered structural and pathologic events along with the interaction of the surrounding environment and luminal flow dynamics contribute to the aneurysm’s development and growth. In this review, we have tried to simplify the complex interaction of a multitude of events in relation to vessel wall in the formation and growth of IAs.

Original language	English
Article number	5964
Journal	Applied Sciences (Switzerland)
Volume	12
Issue number	12
DOIs	https://doi.org/10.3390/app12125964
Publication status	Published - 2022 Jun 1

Keywords

arterial wall
hemodynamics
intracranial aneurysm

ASJC Scopus subject areas

Materials Science(all)
Instrumentation
Engineering(all)
Process Chemistry and Technology
Computer Science Applications
Fluid Flow and Transfer Processes

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10.3390/app12125964

Cite this

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title = "The Cerebral Arterial Wall in the Development and Growth of Intracranial Aneurysms",

abstract = "A considerable number of people harbor intracranial aneurysms (IA), which is a focal or segmental disease of the arterial wall. The pathophysiologic mechanisms of IAs formation, growth, and rupture are complex. The mechanism also differs with respect to the type of aneurysm. In broad aspects, aneurysms may be considered a disease of the vessel wall. In addition to the classic risk factors and the genetic/environmental conditions, altered structural and pathologic events along with the interaction of the surrounding environment and luminal flow dynamics contribute to the aneurysm{\textquoteright}s development and growth. In this review, we have tried to simplify the complex interaction of a multitude of events in relation to vessel wall in the formation and growth of IAs.",

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doi = "10.3390/app12125964",

language = "English",

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T1 - The Cerebral Arterial Wall in the Development and Growth of Intracranial Aneurysms

AU - Abbate, Pasquale Marco

AU - Hasibul Hasan, A. T.M.

AU - Venier, Alice

AU - Vauclin, Vincent

AU - Pizzuto, Silvia

AU - Sgreccia, Alessandro

AU - Di Maria, Federico

AU - Coskun, Oguzhan

AU - Mizutani, Katsuhiro

AU - Rodesch, Georges

AU - Consoli, Arturo

PY - 2022/6/1

Y1 - 2022/6/1

N2 - A considerable number of people harbor intracranial aneurysms (IA), which is a focal or segmental disease of the arterial wall. The pathophysiologic mechanisms of IAs formation, growth, and rupture are complex. The mechanism also differs with respect to the type of aneurysm. In broad aspects, aneurysms may be considered a disease of the vessel wall. In addition to the classic risk factors and the genetic/environmental conditions, altered structural and pathologic events along with the interaction of the surrounding environment and luminal flow dynamics contribute to the aneurysm’s development and growth. In this review, we have tried to simplify the complex interaction of a multitude of events in relation to vessel wall in the formation and growth of IAs.

AB - A considerable number of people harbor intracranial aneurysms (IA), which is a focal or segmental disease of the arterial wall. The pathophysiologic mechanisms of IAs formation, growth, and rupture are complex. The mechanism also differs with respect to the type of aneurysm. In broad aspects, aneurysms may be considered a disease of the vessel wall. In addition to the classic risk factors and the genetic/environmental conditions, altered structural and pathologic events along with the interaction of the surrounding environment and luminal flow dynamics contribute to the aneurysm’s development and growth. In this review, we have tried to simplify the complex interaction of a multitude of events in relation to vessel wall in the formation and growth of IAs.

KW - arterial wall

KW - hemodynamics

KW - intracranial aneurysm

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The Cerebral Arterial Wall in the Development and Growth of Intracranial Aneurysms

Abstract

Keywords

ASJC Scopus subject areas

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