The effect of physiotherapy on hematopoietic stem cell transplantation patients' disuse syndrome

Mitsunobu Yatsunami, Michiyo Kamisako, Ikki Komiyama, Yuriko Takahashi, Satoshi Endo, Aiko Ishikawa, Meigen Liu, Yoshihisa Masakado, Takehiko Mori, Sakiko Kondo, Susumu Watanabe

Research output: Contribution to journalArticlepeer-review


The purpose of this study was to examine the effect of physiotherapy on the disuse syndrome in were hematopoietic stem cell transplantation patients' bioclean room treatment period. The subjects 17 of 35 patients who received hematopoietic stem cell transplantation in a period covering one year. Before and after transplantation, the patient's grip, muscle strength of lower extremity, endurance, amount of hemoglobin, and flexibility were evaluated. The patient did independent practice of muscle strength and stretching in the bioclean room every day. Furthermore, individual practice of muscle strength and stretching was usually carried out together with a physical therapist 3 times per week in the standing position. Compared with before transplantation, muscle strength, endurance, and flexibility fell after transplantation. The amount of Hb before and after transplantation was almost unchanged, and a low value was shown as compared with normal values. In spite of having performed physiotherapy during the bioclean room stay, the physical fitness before transplantation was unmaintainable. It was thought that the main causes were the activity restrictions in the bioclean room. In addition, the influence of adverse drug reaction, corpuscular reduction, undernutrition, and treatment related symptoms were also considered to have played a part.

Original languageEnglish
Pages (from-to)133-138
Number of pages6
JournalRigakuryoho Kagaku
Issue number2
Publication statusPublished - 2005 May


  • Disuse syndrome
  • Hematopoietic stem cell transplantation
  • Physiotherapy

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation


Dive into the research topics of 'The effect of physiotherapy on hematopoietic stem cell transplantation patients' disuse syndrome'. Together they form a unique fingerprint.

Cite this