The isolation and structures of euphoscopins a and b

Shosuke Yamamura; Seiji Kosemura; Shigeru Ohba; Masatoki Ito; Yoshihiko Saito

doi:10.1016/S0040-4039(01)92490-6

The isolation and structures of euphoscopins a and b

Shosuke Yamamura, Seiji Kosemura, Shigeru Ohba, Masatoki Ito, Yoshihiko Saito

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40 Citations (Scopus)

Abstract

Two new toxic substances, euphoscopins A and B, have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the p-bromobenzoate readily obtained on treatment of euphoscopin A with p-bromobenzoyl chloride - pyridine. These antitumor substances belong to a group of jatrophone-type diterpenes.

Original language	English
Pages (from-to)	5315-5318
Number of pages	4
Journal	Tetrahedron Letters
Volume	22
Issue number	52
DOIs	https://doi.org/10.1016/S0040-4039(01)92490-6
Publication status	Published - 1981

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)92490-6

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AU - Yamamura, Shosuke

AU - Kosemura, Seiji

AU - Ohba, Shigeru

AU - Ito, Masatoki

AU - Saito, Yoshihiko

PY - 1981

Y1 - 1981

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AB - Two new toxic substances, euphoscopins A and B, have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the p-bromobenzoate readily obtained on treatment of euphoscopin A with p-bromobenzoyl chloride - pyridine. These antitumor substances belong to a group of jatrophone-type diterpenes.

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

The isolation and structures of euphoscopins a and b

Abstract

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