The Role of Endoscopy in Inflammatory Bowel Disease

Haruhiko Ogata

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Endoscopic assessment of mucosal lesions has emerged as an important concept of disease activity in inflammatory bowel disease (IBD), and recently mucosal healing has generally been regarded as a therapeutic goal not only in ulcerative colitis (UC) but also in Crohn’s disease (CD). Several pieces of evidence have now accumulated to show that mucosal healing determined by endoscopy can alter the course of IBD, as it is associated with sustained clinical remission, and reduced rates of hospitalization and surgical resection. Generally, clinical activity indices established in IBD are mainly determined based on subjective/objective signs and the results of laboratory tests. However, those indices sometimes lead to discrepancy compared with endoscopic indices. Although endoscopy has been rarely investigated as a predictor of the clinical course of IBD, there is now growing evidence that morphological examination, including endoscopy, may help to identify among IBD patients those who should be treated with more intensive treatments. Furthermore, as demonstrated in a recent study assessing early intervention with combination of biologics and immunomodulators, endoscopy may help to select patients who will obtain the best results with early intervention. This chapter summarizes the role of endoscopy in IBD by introducing several modalities such as colonoscopy, balloon-assisted enteroscopy, and video capsule endoscopy, as well as CT colonography and MR enterography.

Original languageEnglish
Title of host publicationAdvances in Endoscopy in Inflammatory Bowel Disease
PublisherSpringer Japan
Pages1-11
Number of pages11
ISBN (Electronic)9784431560180
ISBN (Print)9784431560166
DOIs
Publication statusPublished - 2017 Jan 1

Keywords

  • Activity indices
  • Crohn’s disease
  • Endoscopy
  • Inflammatory bowel disease
  • Medical therapy
  • Mucosal healing
  • Surgery
  • Ulcerative colitis

ASJC Scopus subject areas

  • General Medicine

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