The role of surgery in advanced neuroblastoma

J. Yokoyama, H. Ikawa, M. Endow, Y. Fuchimoto, K. Watanabe, R. Hosoya, K. Nishimura

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Recently we performed multi-modal therapy including chemotherapy with bone marrow transplantation (BMT), surgery, and local irradiation in the treatment of advanced neuroblastoma. As a result, all Stage III patients survived, and 4 out of 8 Stage IV patients who underwent our original systemic gross complete resection achieved long-term survival, 4y8m, 5y8m, and 5y5m, respectively. Long-term survival patients were treated by local irradiation, brain surgery and intensive induction chemotherapy before primary site operation, and when resolution of distal metastases was obtained, the primary site was resected completely, followed by postoperative supralethal chemotherapy with BMT. The purpose of this report is to elucidate the role of surgery in advanced neuroblastoma based on our clinical results.

Original languageEnglish
Pages (from-to)23-26
Number of pages4
JournalEuropean Journal of Pediatric Surgery
Issue number1
Publication statusPublished - 1996 Jan 1


  • Bone marrow transplantation
  • Intensive chemotherapy
  • Neuroblastoma
  • Surgery

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery


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