The surgical treatment of fixed subaortic stenosis: A clinical experience in Japan

Ryo Aeba, Toshiyuki Katogi, Tsutomu Ito, Tetsuya Goto, Yasunori Cho, Yoshito Inoue, Tadashi Omoto, Katsumi Moro, Yoshihisa Nakao, Ryohei Yozu, Shigeyuki Takeuchi, Shiaki Kawada

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


We report herein the results of a retrospective study conducted on ten consecutive Japanese patients who underwent successful surgical relief of fixed subaortic stenosis between 1972 and 1994 at ages ranging from 8 months to 21 years, and followed for 3.6 years and 26 years. Associated cardiovascular defects were present in six patients, two had a history of infective endocarditis, a discrete fibrous ring was found in nine patients, and a redundant abnormal sheet was found in one. A stenotic structure was removed in nine patients and incised in one, while myotomy was additionally performed in one. There were no early complications or deaths. Cardiac catheterization revealed a significant decrease in the peak systolic pressure gradient from 84 ± 22 mmHg preoperatively to 32 ± 22 mmHg postoperatively (P = 0.0017). Reoperation of an aortic valve replacement with or without valvular annulus enlargement was required in four patients because of a small annulus with aortic insufficiency or infective endocarditis. Infective endocarditis was a major cause of late mortality (n = 1) and morbidity (n = 1), but the remaining eight patients have been asymptomatic. Thus, although this lesion is relatively rare in Japan, the typical discrete type maybe more common than previously believed. While a relief operation is associated with low early mortality, the palliative aspect regarding pathology of the aortic valve should not be underestimated, including poor growth of the valve annulus, deterioration of aortic insufficiency, and infective endocarditis. The most appropriate operative procedure for reoperation remains to be evolved.

Original languageEnglish
Pages (from-to)317-321
Number of pages5
JournalSurgery today
Issue number4
Publication statusPublished - 1999


  • Aortic valve annulus enlargement
  • Fixed subaortic stenosis
  • Infective endocarditis

ASJC Scopus subject areas

  • Surgery


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