TY - JOUR
T1 - tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila
AU - Hirota, Yuki
AU - Sawamoto, Kazunobu
AU - Okano, Hideyuki
PY - 2002/12/1
Y1 - 2002/12/1
N2 - We cloned and characterized the Drosophila gene, tincar (tinc), which encodes a novel protein with eight putative transmembrane domains. The tinc mRNA was expressed specifically in four of the six pairs of cardioblasts in each segment, in a pattern identical to that of tinman (tin), a homeobox gene required for the specification of the dorsal vessel. In the non-Tin-expressing pairs of cardioblasts, tinc transcription seemed to be repressed by Seven-up.
AB - We cloned and characterized the Drosophila gene, tincar (tinc), which encodes a novel protein with eight putative transmembrane domains. The tinc mRNA was expressed specifically in four of the six pairs of cardioblasts in each segment, in a pattern identical to that of tinman (tin), a homeobox gene required for the specification of the dorsal vessel. In the non-Tin-expressing pairs of cardioblasts, tinc transcription seemed to be repressed by Seven-up.
KW - Cardioblast
KW - Dorsal vessel
KW - Drosophila
KW - Heart
KW - tincar
KW - tinman
UR - http://www.scopus.com/inward/record.url?scp=0036952039&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036952039&partnerID=8YFLogxK
U2 - 10.1016/S0925-4773(02)00387-8
DO - 10.1016/S0925-4773(02)00387-8
M3 - Article
C2 - 12617821
AN - SCOPUS:0036952039
SN - 1567-133X
VL - 2
SP - 323
EP - 327
JO - Gene Expression Patterns
JF - Gene Expression Patterns
IS - 3-4
ER -