Toad's egg-like cultivation process for forming microcarriers from nanofibrous hydrogel

K. Higashi; Norihisa Miki

doi:10.1109/EMBC.2015.7319734

Toad's egg-like cultivation process for forming microcarriers from nanofibrous hydrogel

K. Higashi, Norihisa Miki

Department of Mechanical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Citations (Scopus)

Abstract

This paper proposes a new method for generating microcarries from bacterial cellulose (BC). BC, which is produced by specific bacteria, is a hydrogel composed of a three dimensional network structure formed by cellulose nanofibers. BC as an ECM-like nanofibrous material exhibits an excellent environment for cellular adhesion. Moreover, BC has a high biocompatibility and mechanical strength. From these properties, BC is expected to be applied for microcarriers, which is used for cultivating anchorage-dependent cells. Then, we developed a microfabrication process to create BC microcarriers by using gelatin microspheres as sacrificial architectures. In addition, the monodispersity of the formed BC microcarreirs was investigated.

Original language	English
Title of host publication	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	5900-5903
Number of pages	4
Volume	2015-November
ISBN (Print)	9781424492718
DOIs	https://doi.org/10.1109/EMBC.2015.7319734
Publication status	Published - 2015 Nov 4
Event	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy Duration: 2015 Aug 25 → 2015 Aug 29

Other

Other	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Country/Territory	Italy
City	Milan
Period	15/8/25 → 15/8/29

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

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10.1109/EMBC.2015.7319734

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Higashi, K., & Miki, N. (2015). Toad's egg-like cultivation process for forming microcarriers from nanofibrous hydrogel. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (Vol. 2015-November, pp. 5900-5903). Article 7319734 Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7319734

Toad's egg-like cultivation process for forming microcarriers from nanofibrous hydrogel. / Higashi, K.; Miki, Norihisa.
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. p. 5900-5903 7319734.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Higashi, K & Miki, N 2015, Toad's egg-like cultivation process for forming microcarriers from nanofibrous hydrogel. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. vol. 2015-November, 7319734, Institute of Electrical and Electronics Engineers Inc., pp. 5900-5903, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 15/8/25. https://doi.org/10.1109/EMBC.2015.7319734

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Toad's egg-like cultivation process for forming microcarriers from nanofibrous hydrogel

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