Total synthesis and stereochemical reassignment of maedamide

Ayano Takayanagi, Arihiro Iwasaki, Kiyotake Suenaga

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Abstract The first total synthesis of maedamide, an acyclic peptide isolated from a marine cyanobacterial assemblage of Lyngbya sp., was achieved. This synthesis led to reassignment of the allo-d-Ile of maedamide to be l-Ile, which was supported by 1H and 13C NMR data.

Original languageEnglish
Article number46482
Pages (from-to)4947-4949
Number of pages3
JournalTetrahedron Letters
Issue number34
Publication statusPublished - 2015 Jul 20


  • Lyngbya
  • Maedamide
  • Marine cyanobacteria
  • Marine natural products
  • Total synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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