Total synthesis of bengamide E

Noritaka Chida, Takahiko Tobe, Seiichiro Ogawa

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)


The first total synthesis of bengamide E (1), a novel sponge-derived amino acid, is described. The side chain of bengamide E (2) possessing four contiguous chiral centers was prepared in a stereoselective manner starting from naturally abundant cyclitol, l-quebrachitol.

Original languageEnglish
Pages (from-to)1063-1066
Number of pages4
JournalTetrahedron Letters
Issue number8
Publication statusPublished - 1991 Feb 18

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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