Total synthesis of (+)-cheimonophyllon E, a bisabolane sesquiterpenoid

Ken Ichi Takao; Manabu Hara; Tomohiro Tsujita; Ken Ichi Yoshida; Kin Ichi Tadano

doi:10.1016/S0040-4039(01)00817-6

Total synthesis of (+)-cheimonophyllon E, a bisabolane sesquiterpenoid

Ken Ichi Takao, Manabu Hara, Tomohiro Tsujita, Ken Ichi Yoshida, Kin Ichi Tadano

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Total synthesis of (±)-cheimonophyllon E was accomplished starting from 3-methyl-2-cyclohexen-1-one. Also, synthesis of (+)-cheimonophyllon E, the natural enantiomer, was achieved through optical resolution of a key intermediate in the racemic synthesis.

Original language	English
Pages (from-to)	4665-4668
Number of pages	4
Journal	Tetrahedron Letters
Volume	42
Issue number	28
DOIs	https://doi.org/10.1016/S0040-4039(01)00817-6
Publication status	Published - 2001 Jul 9

Keywords

Biologically active compounds
Cyclization
Resolution
Terpenes and terpenoids

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)00817-6

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abstract = "Total synthesis of (±)-cheimonophyllon E was accomplished starting from 3-methyl-2-cyclohexen-1-one. Also, synthesis of (+)-cheimonophyllon E, the natural enantiomer, was achieved through optical resolution of a key intermediate in the racemic synthesis.",

keywords = "Biologically active compounds, Cyclization, Resolution, Terpenes and terpenoids",

author = "Takao, {Ken Ichi} and Manabu Hara and Tomohiro Tsujita and Yoshida, {Ken Ichi} and Tadano, {Kin Ichi}",

year = "2001",

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T1 - Total synthesis of (+)-cheimonophyllon E, a bisabolane sesquiterpenoid

AU - Takao, Ken Ichi

AU - Hara, Manabu

AU - Tsujita, Tomohiro

AU - Yoshida, Ken Ichi

AU - Tadano, Kin Ichi

PY - 2001/7/9

Y1 - 2001/7/9

N2 - Total synthesis of (±)-cheimonophyllon E was accomplished starting from 3-methyl-2-cyclohexen-1-one. Also, synthesis of (+)-cheimonophyllon E, the natural enantiomer, was achieved through optical resolution of a key intermediate in the racemic synthesis.

AB - Total synthesis of (±)-cheimonophyllon E was accomplished starting from 3-methyl-2-cyclohexen-1-one. Also, synthesis of (+)-cheimonophyllon E, the natural enantiomer, was achieved through optical resolution of a key intermediate in the racemic synthesis.

KW - Biologically active compounds

KW - Cyclization

KW - Resolution

KW - Terpenes and terpenoids

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U2 - 10.1016/S0040-4039(01)00817-6

DO - 10.1016/S0040-4039(01)00817-6

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 28

ER -

Total synthesis of (+)-cheimonophyllon E, a bisabolane sesquiterpenoid

Abstract

Keywords

ASJC Scopus subject areas

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