Total synthesis of (+)-polyoxin J starting from myo-inositol

Noritaka Chida, Kazue Koizumi, Yoko Kitada, Chiaki Yokoyama, Seiichiro Ogawa

Research output: Contribution to journalArticlepeer-review

71 Citations (Scopus)


The total synthesis of the antifungal antibiotic, polyoxin J 1 starting from myo-inositol is described; the two key components, 2 and 3, were prepared from a pair of optically resolved myo-inositol derivatives 4L and 4D, respectively, using a highly regioselective Baeyer-Villiger reaction, and finally coupled to complete the total synthesis.

Original languageEnglish
Pages (from-to)111-113
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number1
Publication statusPublished - 1994 Dec 1

ASJC Scopus subject areas

  • Molecular Medicine


Dive into the research topics of 'Total synthesis of (+)-polyoxin J starting from myo-inositol'. Together they form a unique fingerprint.

Cite this