Toxic Epidermal Necrolysis with Tracheobronchial and Pulmonary Complications

Tamihiro Kamata, Hirofumi Fujita, Tetsuya Urano, Masaaki Mori, Kazuhiro Yamaguchi, Minoru Kanazawa

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


A 55-year-old man developed multiple erythematous skin lesions after surgery for acoustic neurinoma. Necrosis and detachment of the epidermis developed and a diagnosis of toxic epidermal necrolysis (TEN) was made. Progressive dyspnea was evident two days after the onset of the skin lesions. Chest X-ray revealed diffuse interstitial shadows in both lung fields. On bronchoscopic examination, erosion, vesicle formation, necrosis and desquamation of the epidermis were seen in the tracheobronchial mucosa. Therapy, including prednisolone, improved the skin lesions as well as the chest X-ray and bronchoscopic findings. Tracheobronchial and pulmonary lesions were followed before, during and after treatment of TEN.

Original languageEnglish
Pages (from-to)252-255
Number of pages4
JournalInternal Medicine
Issue number4
Publication statusPublished - 1994


  • interstitial pneumonia
  • toxic epidermal necrolysis
  • tracheobronchial lesion

ASJC Scopus subject areas

  • Internal Medicine


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