Transcutaneous measurement of bio-substances by suction effusion fluid from skin

Shinsuke Kayashima, Tsunenori Arai, Makoto Kikuchi, Naokazu Nagata, Osamu Takatani, Shigeyuki Miyamoto, Shio Shinohara, Narushi Ito, Jun Kimura, Toshihide Kuriyama

Research output: Contribution to journalConference articlepeer-review


Successful transcutaneous blood glucose monitoring on human subjects has been achieved. Effusion fluid is collected from the skin using a recently developed suction apparatus, and glucose concentration in the fluid is measured. During a 75-g oral glucose tolerance test (75 g OGTT) on normal subjects, frequent transcutaneous monitoring of blood glucose change was achieved with an improved ion-sensitive field effect transistor glucose sensor which can measure glucose concentration in only 5-μl samples.

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics


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