Two cases of anaplastic carcinoma of the pancreas in terms of the diversity of carcinoma cells (epithelial-mesenchymal transition; EMT)

Masaru Okamoto; Satoshi Kitajima; Ryuujirou Negishi; Tadateru Maehata; Tsuyoshi Kouro; Shunichi Yamauchi; Hideaki Takahashi; Yoshiki Katakura; Yoshiyuki Watanabe; Ryuichi Abiko; Shinichi Nakaya; Hiroyuki Inaba; Toshifumi Takano; Michihiro Suzuki; Fumio Itoh

Two cases of anaplastic carcinoma of the pancreas in terms of the diversity of carcinoma cells (epithelial-mesenchymal transition; EMT)

Masaru Okamoto, Satoshi Kitajima, Ryuujirou Negishi, Tadateru Maehata, Tsuyoshi Kouro, Shunichi Yamauchi, Hideaki Takahashi, Yoshiki Katakura, Yoshiyuki Watanabe, Ryuichi Abiko, Shinichi Nakaya, Hiroyuki Inaba, Toshifumi Takano, Michihiro Suzuki, Fumio Itoh

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The first evaluated case was a 71-year-old man with melaena. A huge tumor mass was observed in the tale of the pancreas, which we diagnosed as pancreatic carcinoma. Pathological findings confirmed that it was anaplastic pancreas carcinoma (giant cell type). The second case was a 61-year-old woman with upper abdominal pain. Irregular tumors with scattered cysts were observed in the tale of the pancreas, which rapidly increased. Autopsy findings confirmed that it was anaplastic pancreas carcinoma (pleomorphic type). Both cases showed positive for epithelial marker and mesenchymal markers and decrease in stainability by E-cadherin staining, a result which suggested diversity of tumor cells in anaplastic pancreas carcinomas.

Original language	English
Pages (from-to)	1656-1665
Number of pages	10
Journal	Japanese Journal of Gastroenterology
Volume	105
Issue number	11
Publication status	Published - 2008
Externally published	Yes

ASJC Scopus subject areas

Gastroenterology

Cite this

Okamoto, M., Kitajima, S., Negishi, R., Maehata, T., Kouro, T., Yamauchi, S., Takahashi, H., Katakura, Y., Watanabe, Y., Abiko, R., Nakaya, S., Inaba, H., Takano, T., Suzuki, M., & Itoh, F. (2008). Two cases of anaplastic carcinoma of the pancreas in terms of the diversity of carcinoma cells (epithelial-mesenchymal transition; EMT). Japanese Journal of Gastroenterology, 105(11), 1656-1665.

Okamoto, M, Kitajima, S, Negishi, R, Maehata, T, Kouro, T, Yamauchi, S, Takahashi, H, Katakura, Y, Watanabe, Y, Abiko, R, Nakaya, S, Inaba, H, Takano, T, Suzuki, M & Itoh, F 2008, 'Two cases of anaplastic carcinoma of the pancreas in terms of the diversity of carcinoma cells (epithelial-mesenchymal transition; EMT)', Japanese Journal of Gastroenterology, vol. 105, no. 11, pp. 1656-1665.

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abstract = "The first evaluated case was a 71-year-old man with melaena. A huge tumor mass was observed in the tale of the pancreas, which we diagnosed as pancreatic carcinoma. Pathological findings confirmed that it was anaplastic pancreas carcinoma (giant cell type). The second case was a 61-year-old woman with upper abdominal pain. Irregular tumors with scattered cysts were observed in the tale of the pancreas, which rapidly increased. Autopsy findings confirmed that it was anaplastic pancreas carcinoma (pleomorphic type). Both cases showed positive for epithelial marker and mesenchymal markers and decrease in stainability by E-cadherin staining, a result which suggested diversity of tumor cells in anaplastic pancreas carcinomas.",

author = "Masaru Okamoto and Satoshi Kitajima and Ryuujirou Negishi and Tadateru Maehata and Tsuyoshi Kouro and Shunichi Yamauchi and Hideaki Takahashi and Yoshiki Katakura and Yoshiyuki Watanabe and Ryuichi Abiko and Shinichi Nakaya and Hiroyuki Inaba and Toshifumi Takano and Michihiro Suzuki and Fumio Itoh",

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T1 - Two cases of anaplastic carcinoma of the pancreas in terms of the diversity of carcinoma cells (epithelial-mesenchymal transition; EMT)

AU - Okamoto, Masaru

AU - Kitajima, Satoshi

AU - Negishi, Ryuujirou

AU - Maehata, Tadateru

AU - Kouro, Tsuyoshi

AU - Yamauchi, Shunichi

AU - Takahashi, Hideaki

AU - Katakura, Yoshiki

AU - Watanabe, Yoshiyuki

AU - Abiko, Ryuichi

AU - Nakaya, Shinichi

AU - Inaba, Hiroyuki

AU - Takano, Toshifumi

AU - Suzuki, Michihiro

AU - Itoh, Fumio

PY - 2008

Y1 - 2008

N2 - The first evaluated case was a 71-year-old man with melaena. A huge tumor mass was observed in the tale of the pancreas, which we diagnosed as pancreatic carcinoma. Pathological findings confirmed that it was anaplastic pancreas carcinoma (giant cell type). The second case was a 61-year-old woman with upper abdominal pain. Irregular tumors with scattered cysts were observed in the tale of the pancreas, which rapidly increased. Autopsy findings confirmed that it was anaplastic pancreas carcinoma (pleomorphic type). Both cases showed positive for epithelial marker and mesenchymal markers and decrease in stainability by E-cadherin staining, a result which suggested diversity of tumor cells in anaplastic pancreas carcinomas.

AB - The first evaluated case was a 71-year-old man with melaena. A huge tumor mass was observed in the tale of the pancreas, which we diagnosed as pancreatic carcinoma. Pathological findings confirmed that it was anaplastic pancreas carcinoma (giant cell type). The second case was a 61-year-old woman with upper abdominal pain. Irregular tumors with scattered cysts were observed in the tale of the pancreas, which rapidly increased. Autopsy findings confirmed that it was anaplastic pancreas carcinoma (pleomorphic type). Both cases showed positive for epithelial marker and mesenchymal markers and decrease in stainability by E-cadherin staining, a result which suggested diversity of tumor cells in anaplastic pancreas carcinomas.

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SN - 0446-6586

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JO - Japanese Journal of Gastroenterology

JF - Japanese Journal of Gastroenterology

IS - 11

ER -

Two cases of anaplastic carcinoma of the pancreas in terms of the diversity of carcinoma cells (epithelial-mesenchymal transition; EMT)

Abstract

ASJC Scopus subject areas

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