Two new diterpenoids from Leonotis leonurus R. Br.

Yuji Narukawa, Miyuki Komori, Akiko Niimura, Hitomi Noguchi, Fumiyuki Kiuchi

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)


Two new diterpenoids, 14α-hydroxy-9α,13α-epoxylabd-5(6)-en-7-on-16,15-olide (1) and 13ξ-hydroxylabd-5(6),8(9)-dien-7-on-16,15-olide (2) along with six known diterpenoids were isolated from the aerial parts of Leonotis leonurus R. Br. These structures were determined on the basis of spectroscopic analyses. Some of the isolated compounds showed weak to moderate estrogen sulfotransferase inhibitory activity.

Original languageEnglish
Pages (from-to)130-134
Number of pages5
JournalJournal of Natural Medicines
Issue number1
Publication statusPublished - 2015 Jan
Externally publishedYes


  • Diterpenoids
  • Estrogen sulfotransferase
  • Inhibitor
  • Labiatae
  • Leonotis leonurus

ASJC Scopus subject areas

  • Molecular Medicine


Dive into the research topics of 'Two new diterpenoids from Leonotis leonurus R. Br.'. Together they form a unique fingerprint.

Cite this