TY - JOUR
T1 - Two new monoterpene glycosides and trypanocidal terpenoids from Dracocephalum kotschyi
AU - Saeidnia, Soodabeh
AU - Gohari, Ahmad Reza
AU - Uchiyama, Nahoko
AU - Ito, Michiho
AU - Honda, Gisho
AU - Kiuchi, Fumiyuki
PY - 2004/10
Y1 - 2004/10
N2 - From the whole plant of Dracocephalum kotschyi BOISS., two new monoterpene glycosides (9, 10), together with seven known terpenoids and a phytosterol (1-8), were isolated. Their structures were determined to be limonen-10-al (1), geranial (2), neral (3), β-sitosterol (4), oleanolic acid (5), ursolic acid (6), p-mentha-8-en-1,2-diol (7), colosolic acid (8), limonen-10-ol 10-O-β-D-glucopyranoside (9), and limonen-10-ol 10-O-β-D- glucopyranosyl-(1→2)-β-D-glucopyranoside (10). Compounds 1 (3.1 μM), 2 (3.1 μM), 3 (3.1 μM), 5 (6.2 μM), 6 (6.2 μM), and 8 (6.2 μM) were effective against epimastigotes of Trypanosoma cruzi.
AB - From the whole plant of Dracocephalum kotschyi BOISS., two new monoterpene glycosides (9, 10), together with seven known terpenoids and a phytosterol (1-8), were isolated. Their structures were determined to be limonen-10-al (1), geranial (2), neral (3), β-sitosterol (4), oleanolic acid (5), ursolic acid (6), p-mentha-8-en-1,2-diol (7), colosolic acid (8), limonen-10-ol 10-O-β-D-glucopyranoside (9), and limonen-10-ol 10-O-β-D- glucopyranosyl-(1→2)-β-D-glucopyranoside (10). Compounds 1 (3.1 μM), 2 (3.1 μM), 3 (3.1 μM), 5 (6.2 μM), 6 (6.2 μM), and 8 (6.2 μM) were effective against epimastigotes of Trypanosoma cruzi.
KW - Dracocephalum kotschyi
KW - Monoterpene glucoside
KW - Trypanocidal activity
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U2 - 10.1248/cpb.52.1249
DO - 10.1248/cpb.52.1249
M3 - Article
C2 - 15467247
AN - SCOPUS:14944346702
SN - 0009-2363
VL - 52
SP - 1249
EP - 1250
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
IS - 10
ER -