Urinary catecholamine excretion during gynecological laparoscopy

H. Morisaki, Y. Takino, J. Takahashi, S. Iwanami

Research output: Contribution to journalArticlepeer-review


In 10 patients with ages ranging between 23 and 37 undergoing elective gynecological laparoscopy under pethidine-N2O-pancuronium anesthesia, we measured excretion of norepinephrine (NE) and epinephrine (EN) per 1 mg of urine creatinine in order to evaluate the sympathetic effect of this surgical procedure. Catecholamines were analysed by high-performance liquid chromatography using native fluorescence technique. During laparoscopy, we observed a significant increase in NE and EN excretion (from 73 ± 32 ng/mg·cr to 151 ± 89 ng/mg·Cr and from 24 ± 16 ng/mg·Cr to 39 ± 22 ng/mg·Cr, respectively, mean ± SD). Such increases are considered to be beneficial in maintaining arterial pressure in these cases, where considerable reduction in cardiac output caused by high intraabdominal pressure is expected.

Original languageEnglish
Pages (from-to)636-638
Number of pages3
JournalJapanese Journal of Anesthesiology
Issue number4
Publication statusPublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


Dive into the research topics of 'Urinary catecholamine excretion during gynecological laparoscopy'. Together they form a unique fingerprint.

Cite this