TY - JOUR
T1 - Utilisation of L-quebrachitol in natural product synthesis. Total synthesis and absolute configuration of (-)-oudemansin X
AU - Chida, Noritaka
AU - Yamada, Ken
AU - Ogawa, Seiichiro
PY - 1993
Y1 - 1993
N2 - The stereoselective conversion of the naturally occurring optically active cyclitol, L-quebrachitol 2, into antifungal β-methoxyacrylate, oudemansin X 1 is described. This first total synthesis of 1 fully confirmed the proposed absolute configuration of the antibiotic and showed the importance of 2 as a versatile chiral starting material in natural product syntheses.
AB - The stereoselective conversion of the naturally occurring optically active cyclitol, L-quebrachitol 2, into antifungal β-methoxyacrylate, oudemansin X 1 is described. This first total synthesis of 1 fully confirmed the proposed absolute configuration of the antibiotic and showed the importance of 2 as a versatile chiral starting material in natural product syntheses.
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U2 - 10.1039/p19930001957
DO - 10.1039/p19930001957
M3 - Article
AN - SCOPUS:37049076629
SN - 1472-7781
SP - 1957
EP - 1962
JO - Journal of the Chemical Society, Perkin Transactions 1
JF - Journal of the Chemical Society, Perkin Transactions 1
IS - 17
ER -