TY - GEN
T1 - Vertical and horizontal confocal imaging of single cells on magnetically handleable microplates
AU - Teshima, T.
AU - Aonuma, H.
AU - Onoe, H.
AU - Kanuka, H.
AU - Takeuchi, S.
PY - 2013
Y1 - 2013
N2 - In this study, we purpose the microfabricated system to manipulate single host cells of parasites toward the analysis of invasion at single cell level. We fabricated the microplates made from Parylene and modified the shape and structure of surface by using lithography techniques. This device is able to not only control the shape and morphology of adhering host cells, but also handle them maintaining their adherent property. The ability to manipulate single adherent host cells reveals the unknown triggered key for parasite invasion. This method can be an attractive platform for the manipulation of host cells, the observation of invading microbes and the analysis of interaction between microbe and host cells.
AB - In this study, we purpose the microfabricated system to manipulate single host cells of parasites toward the analysis of invasion at single cell level. We fabricated the microplates made from Parylene and modified the shape and structure of surface by using lithography techniques. This device is able to not only control the shape and morphology of adhering host cells, but also handle them maintaining their adherent property. The ability to manipulate single adherent host cells reveals the unknown triggered key for parasite invasion. This method can be an attractive platform for the manipulation of host cells, the observation of invading microbes and the analysis of interaction between microbe and host cells.
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U2 - 10.1109/MEMSYS.2013.6474198
DO - 10.1109/MEMSYS.2013.6474198
M3 - Conference contribution
AN - SCOPUS:84875425416
SN - 9781467356558
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 145
EP - 148
BT - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
T2 - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Y2 - 20 January 2013 through 24 January 2013
ER -