Water-vapor permeability control of PDMS by the dispersion of collagen powder

Yuhua Zhang, Masatoshi Ishida, Yutaka Kazoe, Yohei Sato, Norihisa Miki

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)


Polydimethylsiloxane (PDMS) has been widely used as a material for micro-total analysis system (μTAS) devices due to the superior nature of its manufacturability and chemical resistance, etc. PDMS is known to allow the permeation of gas and water vapor. This characteristic was applied to ensure an efficient oxygen supply to cells cultivated in micro-chambers and power-free sample injection into micro-fluidic devices. Some applications, such as long-term experiments with aqueous samples, however, prefer to avert the permeation of water vapor through PDMS. This paper reports on a new method to control the water-vapor permeability of PDMS by dispersing collagen powder (collagen/PDMS polymer). First, we evaluated the manufacturability and material strength of the collagen/PDMS polymer to see whether the polymer could be employed as a material for μTAS devices. Subsequently, we designed and fabricated micro-fluidic devices to directly measure the amount of water vapor permeating through a PDMS or collagen/PDMS membrane, and evaluated the effect of the dispersed collagen. The use of the dispersed collagen powder successfully reduced the water-vapor permeability of PDMS by 54%.

Original languageEnglish
Pages (from-to)442-449
Number of pages8
JournalIEEJ Transactions on Electrical and Electronic Engineering
Issue number3
Publication statusPublished - 2009 May


  • Collagen
  • Material
  • Polydimethylsiloxane
  • Water permeability
  • μTAS

ASJC Scopus subject areas

  • Electrical and Electronic Engineering


Dive into the research topics of 'Water-vapor permeability control of PDMS by the dispersion of collagen powder'. Together they form a unique fingerprint.

Cite this