“Worldwide Network for Blood & Marrow Transplantation (WBMT) special article, challenges facing emerging alternate donor registries”

Mahmoud Aljurf, Daniel Weisdorf, Feras Alfraih, Jeff Szer, Carlheinz Müller, Dennis Confer, Shahrukh Hashmi, Nicolaus Kröger, Bronwen E. Shaw, Hildegard Greinix, Mohamed A. Kharfan-Dabaja, Lydia Foeken, Adriana Seber, Syed Ahmed, Areej El-Jawahri, Moheeb Al-Awwami, Yoshiko Atsuta, Marcelo Pasquini, Amr Hanbali, Hazzaa AlzahraniShinichiro Okamoto, Eliane Gluckman, Mohamad Mohty, Yoshihisa Kodera, Mary Horowitz, Dietger Niederwieser, Riad El Fakih

Research output: Contribution to journalReview articlepeer-review

41 Citations (Scopus)


Hematopoietic cell transplantation (HCT) activity is increasing at an unprecedented pace with > 50,000 allogeneic transplants occurring annually worldwide. Establishing a functional HCT donor registry can be very challenging with respect to ethnicities, financial, technical, and geopolitical issues. Extensive planning steps are essential to overcome the expected challenges while establishing the registry, and to maintain its functionality. A few strategies can help move past those challenges and push the development of such registries forward. Authorities involved in HCT donor registry establishment will have to balance the advantages and costs of such a project and accommodate the emerging alternatives such as cord blood or related haploidentical transplants. Miscalculations and incomplete understanding of the various aspects of the process can have tremendous impact on the optimization of a HCT donor registry especially in developing countries. Herein we present some challenges in establishing such a registry and present potential solutions.

Original languageEnglish
Pages (from-to)1179-1188
Number of pages10
JournalBone Marrow Transplantation
Issue number8
Publication statusPublished - 2019 Aug 1

ASJC Scopus subject areas

  • Hematology
  • Transplantation


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