年別の研究成果
年別の研究成果
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2023
Acceleration of the Development of Microcirculation Embolism in the Brain due to Capillary Narrowing
Murata, J., Unekawa, M., Kudo, Y., Kotani, M., Kanno, I., Izawa, Y., Tomita, Y., Tanaka, K. F., Nakahara, J. & Masamoto, K., 2023 8月 1, In: Stroke. 54, 8, p. 2135-2144 10 p.研究成果: Article › 査読
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A novel tdTomato transgenic mouse model to visualize FAP-positive cancer-associated fibroblasts
Wei, F., Uchihara, T., Yonemura, A., Yasuda-Yoshihara, N., Yasuda, T., Semba, T., Fukuda, M., Akiyama, T., Kitamura, F., Bu, L., Hu, X., Fu, L., Zhang, J., Kariya, R., Yamasaki, J., Aihara, K., Yamashita, K., Nagano, O., Okada, S., Baba, H., & 1 others, 2023 5月, In: FEBS Journal. 290, 10, p. 2604-2615 12 p.研究成果: Article › 査読
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CD83 expression characterizes precursor exhausted T cell population
Wu, Z., Yoshikawa, T., Inoue, S., Ito, Y., Kasuya, H., Nakashima, T., Zhang, H., Kotaka, S., Hosoda, W., Suzuki, S. & Kagoya, Y., 2023 12月, In: Communications biology. 6, 1, 258.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment
Fan, Y., Li, Y., Yao, X., Jin, J., Scott, A., Liu, B., Wang, S., Huo, L., Wang, Y., Wang, R., Pool Pizzi, M., Ma, L., Shao, S., Sewastjanow-Silva, M., Waters, R., Chatterjee, D., Liu, B., Shanbhag, N., Peng, G., Calin, G. A., & 11 others, 2023 4月, In: Gut. 72, 4, p. 624-637 14 p.研究成果: Article › 査読
5 被引用数 (Scopus) -
Mesolimbic dopamine release precedes actively sought aversive stimuli in mice
Yawata, Y., Shikano, Y., Ogasawara, J., Makino, K., Kashima, T., Ihara, K., Yoshimoto, A., Morikawa, S., Yagishita, S., Tanaka, K. F. & Ikegaya, Y., 2023 12月, In: Nature communications. 14, 1, 2433.研究成果: Article › 査読
Open Access -
Pupil Dynamics-derived Sleep Stage Classification of a Head-fixed Mouse Using a Recurrent Neural Network
Kobayashi, G., Tanaka, K. F. & Takata, N., 2023, In: Keio Journal of Medicine. 72, 2, p. 44-59 16 p.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Separate optogenetic manipulation of Nerve/glial antigen 2 (NG2) glia and mural cells using the NG2 promoter
Oishi, M., Passlick, S., Yamazaki, Y., Unekawa, M., Adachi, R., Yamada, M., Imayoshi, I., Abe, Y., Steinhäuser, C. & Tanaka, K. F., 2023 2月, In: Glia. 71, 2, p. 317-333 17 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Serotonergic neurons control cortical neuronal intracellular energy dynamics by modulating astrocyte-neuron lactate shuttle
Natsubori, A., Hirai, S., Kwon, S., Ono, D., Deng, F., Wan, J., Miyazawa, M., Kojima, T., Okado, H., Karashima, A., Li, Y., Tanaka, K. F. & Honda, M., 2023 1月 20, In: iScience. 26, 1, 105830.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Slow-rising and fast-falling dopaminergic dynamics jointly adjust negative prediction error in the ventral striatum
Shikano, Y., Yagishita, S., Tanaka, K. F. & Takata, N., 2023, (Accepted/In press) In: European Journal of Neuroscience.研究成果: Article › 査読
Open Access3 被引用数 (Scopus) -
Starburst amacrine cells amplify optogenetic visual restoration through gap junctions
Katada, Y., Kunimi, H., Serizawa, N., Lee, D., Kobayashi, K., Negishi, K., Okano, H., Tanaka, K. F., Tsubota, K. & Kurihara, T., 2023 9月 14, In: Molecular Therapy - Methods and Clinical Development. 30, p. 1-13 13 p.研究成果: Article › 査読
Open Access -
Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic Tumors
Akiyama, T., Yasuda, T., Uchihara, T., Yasuda-Yoshihara, N., Tan, B. J. Y., Yonemura, A., Semba, T., Yamasaki, J., Komohara, Y., Ohnishi, K., Wei, F., Fu, L., Zhang, J., Kitamura, F., Yamashita, K., Eto, K., Iwagami, S., Tsukamoto, H., Umemoto, T., Masuda, M., & 6 others, 2023 3月 2, In: Cancer Research. 83, 5, p. 753-770 18 p.研究成果: Article › 査読
6 被引用数 (Scopus) -
2022
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning
Amo, R., Matias, S., Yamanaka, A., Tanaka, K. F., Uchida, N. & Watabe-Uchida, M., 2022 8月, In: Nature Neuroscience. 25, 8, p. 1082-1092 11 p.研究成果: Article › 査読
6 被引用数 (Scopus) -
Angiopoietin-like 4 promotes glucose metabolism by regulating glucose transporter expression in colorectal cancer
Mizuno, S., Seishima, R., Yamasaki, J., Hattori, K., Ogiri, M., Matsui, S., Shigeta, K., Okabayashi, K., Nagano, O., Li, L. & Kitagawa, Y., 2022 6月, In: Journal of Cancer Research and Clinical Oncology. 148, 6, p. 1351-1361 11 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Development of an in vitro carcinogenesis model of human papillomavirus-induced cervical adenocarcinoma
Zhang, M., Kiyono, T., Aoki, K., Goshima, N., Kobayashi, S., Hiranuma, K., Shiraishi, K., Saya, H. & Nakahara, T., 2022 3月, In: Cancer science. 113, 3, p. 904-915 12 p.研究成果: Article › 査読
Open Access4 被引用数 (Scopus) -
Downregulation of B d nf Expression in Adult Mice Causes Body Weight Gain
Suzuki, T. & Tanaka, K. F., 2022 9月, In: Neurochemical Research.研究成果: Article › 査読
1 被引用数 (Scopus) -
Dysfunction of parvalbumin-expressing cells in the thalamic reticular nucleus induces cortical spike-and-wave discharges and an unconscious state
Abdelaal, M. S., Midorikawa, M., Suzuki, T., Kobayashi, K., Takata, N., Miyata, M., Mimura, M. & Tanaka, K. F., 2022, In: Brain Communications. 4, 2, fcac010.研究成果: Article › 査読
Open Access3 被引用数 (Scopus) -
Gene therapy using genome-edited iPS cells for targeting malignant glioma
Tamura, R., Miyoshi, H., Imaizumi, K., Yo, M., Kase, Y., Sato, T., Sato, M., Morimoto, Y., Sampetrean, O., Kohyama, J., Shinozaki, M., Miyawaki, A., Yoshida, K., Saya, H., Okano, H. & Toda, M., 2022, (Accepted/In press) In: Bioengineering and Translational Medicine.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Immune evasion and chronological decrease in titer of neutralizing antibody against SARS-CoV-2 and its variants of concerns in COVID-19 patients
for the Keio Donner Project, 2022 5月, In: Clinical Immunology. 238, 108999.研究成果: Article › 査読
Open Access8 被引用数 (Scopus) -
Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice
Takahashi, A., Durand-de Cuttoli, R., Flanigan, M. E., Hasegawa, E., Tsunematsu, T., Aleyasin, H., Cherasse, Y., Miya, K., Okada, T., Keino-Masu, K., Mitsui, K., Li, L., Patel, V., Blitzer, R. D., Lazarus, M., Tanaka, K. F., Yamanaka, A., Sakurai, T., Ogawa, S. & Russo, S. J., 2022 12月, In: Nature communications. 13, 1, 4039.研究成果: Article › 査読
Open Access4 被引用数 (Scopus) -
MEK inhibition suppresses metastatic progression of KRAS-mutated gastric cancer
Yamasaki, J., Hirata, Y., Otsuki, Y., Suina, K., Saito, Y., Masuda, K., Okazaki, S., Ishimoto, T., Saya, H. & Nagano, O., 2022 3月, In: Cancer science. 113, 3, p. 916-925 10 p.研究成果: Article › 査読
Open Access5 被引用数 (Scopus) -
Mutation of PTPN11 (Encoding SHP-2) Promotes MEK Activation and Malignant Progression in Neurofibromin-Deficient Cells in a Manner Sensitive to BRAP Mutation
Harigai, R., Sato, R., Hirose, C., Takenouchi, T., Kosaki, K., Hirose, T., Saya, H. & Arima, Y., 2022 5月 1, In: Cancers. 14, 10, 2377.研究成果: Article › 査読
Open Access -
Optogenetic stimulus-triggered acquisition of seizure resistance
Shimoda, Y., Beppu, K., Ikoma, Y., Morizawa, Y. M., Zuguchi, S., Hino, U., Yano, R., Sugiura, Y., Moritoh, S., Fukazawa, Y., Suematsu, M., Mushiake, H., Nakasato, N., Iwasaki, M., Tanaka, K. F., Tominaga, T. & Matsui, K., 2022 2月, In: Neurobiology of Disease. 163, 105602.研究成果: Article › 査読
Open Access6 被引用数 (Scopus) -
Oscillatory Population-Level Activity of Dorsal Raphe Serotonergic Neurons Is Inscribed in Sleep Structure
Kato, T., Mitsukura, Y., Yoshida, K., Mimura, M., Takata, N. & Tanaka, K. F., 2022 9月 21, In: Journal of Neuroscience. 42, 38, p. 7244-7255 12 p.研究成果: Article › 査読
Open Access3 被引用数 (Scopus) -
Presence of spontaneous epithelial-mesenchymal plasticity in esophageal cancer
Tsuchihashi, K., Hirata, Y., Yamasaki, J., Suina, K., Tanoue, K., Yae, T., Masuda, K., Baba, E., Akashi, K., Kitagawa, Y., Saya, H. & Nagano, O., 2022 7月, In: Biochemistry and Biophysics Reports. 30, 101246.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Ratio-metric measurement of intracellular calcium in visceral muscles via selective expression of a yellow cameleon calcium sensor
Takai, C., Iwata, N., Kanemaru, K., Tanaka, K. F., Yu, Y., Iino, S. & Nakayama, S., 2022 8月 1, In: Sensors and Actuators B: Chemical. 364, 131756.研究成果: Article › 査読
Open Access -
Rhythmic activation of excitatory neurons in the mouse frontal cortex improves the prefrontal cortex-mediated cognitive function
Hazra, D., Yoshinaga, S., Yoshida, K., Takata, N., Tanaka, K. F., Kubo, K. & Nakajima, K., 2022 11月 21, In: Cerebral cortex (New York, N.Y. : 1991). 32, 23, p. 5243-5258 16 p.研究成果: Article › 査読
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Synaptic pruning through glial synapse engulfment upon motor learning
Morizawa, Y. M., Matsumoto, M., Nakashima, Y., Endo, N., Aida, T., Ishikane, H., Beppu, K., Moritoh, S., Inada, H., Osumi, N., Shigetomi, E., Koizumi, S., Yang, G., Hirai, H., Tanaka, K., Tanaka, K. F., Ohno, N., Fukazawa, Y. & Matsui, K., 2022 11月, In: Nature Neuroscience. 25, 11, p. 1458-1469 12 p.研究成果: Article › 査読
6 被引用数 (Scopus) -
The Mlc1 Promoter Directs Müller Cell-specific Gene Expression in the Retina
Danjo, Y., Shinozaki, Y., Natsubori, A., Kubota, Y., Kashiwagi, K., Tanaka, K. F. & Koizumi, S., 2022 1月, In: Translational Vision Science and Technology. 11, 1, 25.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Tumor-specific interendothelial adhesion mediated by FLRT2 facilitates cancer aggressiveness
Ando, T., Tai-Nagara, I., Sugiura, Y., Kusumoto, D., Okabayashi, K., Kido, Y., Sato, K., Saya, H., Navankasattusas, S., Li, D. Y., Suematsu, M., Kitagawa, Y., Seiradake, E., Yamagishi, S. & Kubota, Y., 2022 3月 15, In: Journal of Clinical Investigation. 132, 6, e153626.研究成果: Article › 査読
Open Access7 被引用数 (Scopus) -
Young age, female sex, and presence of systemic adverse reactions are associated with high post-vaccination antibody titer after two doses of BNT162b2 mRNA SARS-CoV-2 vaccination: An observational study of 646 Japanese healthcare workers and university staff
for the Keio Donner Project Team, 2022 2月 11, In: Vaccine. 40, 7, p. 1019-1025 7 p.研究成果: Article › 査読
Open Access27 被引用数 (Scopus) -
2021
Activation of ventral CA1 hippocampal neurons projecting to the lateral septum during feeding
Kosugi, K., Yoshida, K., Suzuki, T., Kobayashi, K., Yoshida, K., Mimura, M. & Tanaka, K. F., 2021 3月, In: Hippocampus. 31, 3, p. 294-304 11 p.研究成果: Article › 査読
Open Access12 被引用数 (Scopus) -
A Novel Alaska Pollock Gelatin Sealant Shows Higher Bonding Strength and Nerve Regeneration Comparable to That of Fibrin Sealant in a Cadaveric Model and a Rat Model
Masuda, S., Suzuki, T., Shibata, S., Moritoki, N., Abe, Y., Chen, X., Mizuno, Y., Nishiguchi, A., Kimura, H., Matsumura, N., Iwamoto, T., Taguchi, T., Matsumoto, M. & Nakamura, M., 2021 11月 1, In: Plastic and Reconstructive Surgery. 148, 5, p. 742E-752E研究成果: Article › 査読
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Assessment of humoral responses in COVID-19 using various quantitative antibody tests
Wakui, M., Uwamino, Y., Kurafuji, T., Noguchi, M., Ohno, A., Yokota, H., Kikuchi, H., Hasegawa, N., Saya, H. & Murata, M., 2021 7月, In: Annals of Clinical Biochemistry. 58, 4, p. 368-376 9 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Astrocytic cAMP modulates memory via synaptic plasticity
Zhou, Z., Okamoto, K., Onodera, J., Hiragi, T., Andoh, M., Ikawa, M., Tanaka, K. F., Ikegaya, Y. & Koyama, R., 2021 1月 15, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 3, e2016584118.研究成果: Article › 査読
Open Access35 被引用数 (Scopus) -
CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression
Thanee, M., Dokduang, H., Kittirat, Y., Phetcharaburanin, J., Klanrit, P., Titapun, A., Namwat, N., Khuntikeo, N., Wangwiwatsin, A., Saya, H. & Loilome, W., 2021 3月, In: PloS one. 16, 3 March, e0245871.研究成果: Article › 査読
Open Access7 被引用数 (Scopus) -
Chronic social defeat stress impairs goal-directed behavior through dysregulation of ventral hippocampal activity in male mice
Yoshida, K., Drew, M. R., Kono, A., Mimura, M., Takata, N. & Tanaka, K. F., 2021 8月, In: Neuropsychopharmacology. 46, 9, p. 1606-1616 11 p.研究成果: Article › 査読
Open Access11 被引用数 (Scopus) -
Clinical utility of SARS-CoV-2 whole genome sequencing in deciphering source of infection
Keio Donner Project, 2021 1月, In: Journal of Hospital Infection. 107, p. 40-44 5 p.研究成果: Article › 査読
16 被引用数 (Scopus) -
Compartmentalized Input–Output Organization of Lugaro Cells in the Cerebellar Cortex
Miyazaki, T., Yamasaki, M., Tanaka, K. F. & Watanabe, M., 2021 5月 10, In: Neuroscience. 462, p. 89-105 17 p.研究成果: Article › 査読
8 被引用数 (Scopus) -
Comprehensive genomic analysis contrasting primary colorectal cancer and matched liver metastases
Shiomi, A., Kusuhara, M., Sugino, T., Sugiura, T., Ohshima, K., Nagashima, T., Urakami, K., Serizawa, M., Saya, H. & Yamaguchi, K., 2021 6月, In: Oncology Letters. 21, 6, 466.研究成果: Article › 査読
Open Access5 被引用数 (Scopus) -
Deficiency of large tumor suppressor kinase 1 causes congenital hearing loss associated with cochlear abnormalities in mice
Nishiyama, T., Fujioka, M., Saegusa, C., Oishi, N., Harada, T., Hosoya, M., Saya, H. & Ogawa, K., 2021 1月 1, In: Biochemical and Biophysical Research Communications. 534, p. 921-926 6 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Differential pial and penetrating arterial responses examined by optogenetic activation of astrocytes and neurons
Hatakeyama, N., Unekawa, M., Murata, J., Tomita, Y., Suzuki, N., Nakahara, J., Takuwa, H., Kanno, I., Matsui, K., Tanaka, K. F. & Masamoto, K., 2021 10月, In: Journal of Cerebral Blood Flow and Metabolism. 41, 10, p. 2676-2689 14 p.研究成果: Article › 査読
10 被引用数 (Scopus) -
Direct impact of motor cortical stimulation on the blood oxygen-level dependent response in rats
Xin, Z., Abe, Y., Liu, S., Tanaka, K. F., Hosomi, K., Saitoh, Y. & Sekino, M., 2021, In: Magnetic Resonance in Medical Sciences. 20, 1, p. 83-90 8 p.研究成果: Article › 査読
Open Access -
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
FANTOM consortium, 2021 12月 1, In: Nature communications. 12, 1, 3297.研究成果: Article › 査読
Open Access6 被引用数 (Scopus) -
Elevated cellular PpIX potentiates sonodynamic therapy in a mouse glioma stem cell-bearing glioma model by downregulating the Akt/NF-κB/MDR1 pathway
Shono, K., Mizobuchi, Y., Yamaguchi, I., Nakajima, K., Fujiwara, Y., Fujihara, T., Kitazato, K., Matsuzaki, K., Uto, Y., Sampetrean, O., Saya, H. & Takagi, Y., 2021 12月, In: Scientific reports. 11, 1, 15105.研究成果: Article › 査読
Open Access7 被引用数 (Scopus) -
Evaluation of the usability of various rapid antibody tests in the diagnostic application for COVID-19
for the Keio Donner Project Team, 2021 5月, In: Annals of Clinical Biochemistry. 58, 3, p. 174-180 7 p.研究成果: Article › 査読
Open Access15 被引用数 (Scopus) -
Exacerbation of epilepsy by astrocyte alkalization and gap junction uncoupling
Onodera, M., Meyer, J., Furukawa, K., Hiraoka, Y., Aida, T., Tanaka, K., Tanaka, K. F., Rose, C. R. & Matsui, K., 2021 3月 10, In: Journal of Neuroscience. 41, 10, p. 2106-2118 13 p.研究成果: Article › 査読
Open Access23 被引用数 (Scopus) -
Flexible annotation atlas of the mouse brain: combining and dividing brain structures of the Allen Brain Atlas while maintaining anatomical hierarchy
Takata, N., Sato, N., Komaki, Y., Okano, H. & Tanaka, K. F., 2021 12月, In: Scientific reports. 11, 1, 6234.研究成果: Article › 査読
Open Access4 被引用数 (Scopus) -
FOXO3 is a latent tumor suppressor for FOXO3-positive and cytoplasmic-type gastric cancer cells
Tsuji, T., Maeda, Y., Kita, K., Murakami, K., Saya, H., Takemura, H., Inaki, N., Oshima, M. & Oshima, H., 2021 4月 29, In: Oncogene. 40, 17, p. 3072-3086 15 p.研究成果: Article › 査読
Open Access13 被引用数 (Scopus) -
Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice
Miyata, S., Kakizaki, T., Fujihara, K., Obinata, H., Hirano, T., Nakai, J., Tanaka, M., Itohara, S., Watanabe, M., Tanaka, K. F., Abe, M., Sakimura, K. & Yanagawa, Y., 2021 12月, In: Molecular brain. 14, 1, 5.研究成果: Article › 査読
Open Access7 被引用数 (Scopus) -
Heterogeneous Glioma Cell Invasion under Interstitial Flow Depending on Their Differentiation Status
Namba, N., Chonan, Y., Nunokawa, T., Sampetrean, O., Saya, H. & Sudo, R., 2021 4月, In: Tissue Engineering - Part A. 27, 7-8, p. 467-478 12 p.研究成果: Article › 査読
Open Access6 被引用数 (Scopus)