医学教育統轄センター

2025

Clinical Impact of Neoadjuvant Therapy for Resectable Pancreatic Ductal Adenocarcinoma: A Single-Center Retrospective Study

Shimane, G., Kitago, M., Yagi, H., Abe, Y., Hasegawa, Y., Hori, S., Tanaka, M., Tsuzaki, J., Yokoyama, Y., Masugi, Y., Takemura, R. & Kitagawa, Y., 2025 4月, In: Annals of Surgical Oncology. 32, 4, p. 2830-2840 11 p.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Culture and context in Interprofessional education: Expectations in Australia and Japan

Kent, F. & Haruta, J., 2025 1月, In: Medical Education. 59, 1, p. 83-87 5 p.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Do family physicians develop ambiguity tolerance as they gain experience? A multicenter cross-sectional study

Fujikawa, H., Aoki, T., Ando, T. & Haruta, J., 2025, (Accepted/In press) In: Journal of General and Family Medicine.

研究成果: Article › 査読

Open Access

Effective calcineurin inhibitor treatment in adult-onset steroid-resistant nephrotic syndrome with a novel splice donor site variant of TRPC6: a case report

Nagasaka, T., Uchiyama, K., Hama, E. Y., Kojima, D., Kaneko, K., Yoshimoto, N., Yasuda, I., Yamada, M., Miya, F., Suzuki, H., Tajima, T., Yamaguchi, S., Hayashi, K., Kanda, T., Hashiguchi, A., Kosaki, K. & Itoh, H., 2025 4月, In: CEN case reports. 14, 2, p. 208-216 9 p., 100531.

研究成果: Article › 査読

Maternal circadian rhythms during pregnancy dictate metabolic plasticity in offspring

Yao, N., Kinouchi, K., Katoh, M., Ashtiani, K. C., Abdelkarim, S., Morimoto, H., Torimitsu, T., Kozuma, T., Iwahara, A., Kosugi, S., Komuro, J., Kato, K., Tonomura, S., Nakamura, T., Itoh, A., Yamaguchi, S., Yoshino, J., Irie, J., Hashimoto, H. & Yuasa, S. & 8 others, Satoh, A., Mikami, Y., Uchida, S., Ueki, T., Nomura, S., Baldi, P., Hayashi, K. & Itoh, H., 2025 2月 4, In: Cell Metabolism. 37, 2, p. 395-412.e6

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

New criteria for preoperative liver function assessment with safety margins to avoid postoperative mortality during liver resection for hilar cholangiocarcinoma

Kojima, H., Abe, Y., Udagawa, D., Hayashi, K., Chiba, N., Imai, S., Mihara, K., Higashi, H., Odaira, M., Oshima, G., Koizumi, W., Kitago, M., Yagi, H., Hasegawa, Y., Hori, S., Tanaka, M., Nakano, Y., Kawachi, S. & Kitagawa, Y., 2025 2月, In: HPB. 27, 2, p. 159-166 8 p.

研究成果: Article › 査読

Open-Label, Randomized, Controlled, Crossover Trial on the Effect of Dapagliflozin in Patients With ADPKD Receiving Tolvaptan

Uchiyama, K., Kamano, D., Nagasaka, T., Hama, E. Y., Shirai, R., Sumura, R., Kusahana, E., Yanai, A., Nakayama, T., Kimura, T., Takahashi, R., Kasai, T., Tajima, T., Hosoya, K., Azegami, T., Yamaguchi, S., Yoshino, J., Ito, J., Hayashi, M. & Kanda, T. & 4 others, Ishibashi, Y., Washida, N., Itoh, H. & Hayashi, K., 2025 4月, In: Kidney International Reports. 10, 4, p. 1063-1075 13 p.

研究成果: Article › 査読

Open Access

2024

Adipocyte-specific inactivation of NAMPT, a key NAD⁺ biosynthetic enzyme, causes a metabolically unhealthy lean phenotype in female mice during aging

Qi, N., Franczyk, M. P., Yamaguchi, S., Kojima, D., Hayashi, K., Satoh, A., Ogiso, N., Kanda, T., Sasaki, Y., Finck, B. N., DeBosch, B. J. & Yoshino, J., 2024 7月, In: American Journal of Physiology - Endocrinology and Metabolism. 327, 1, p. E81-E88

研究成果: Article › 査読

1 被引用数 (Scopus)

A multi-institutional study designed by members of Tokyo Guidelines (TG) Core Meeting to elucidate the clinical characteristics and pathogenesis of acute cholangitis after bilioenteric anastomosis and biliary stent insertion with a focus on biliary obstruction: Role of transient hepatic attenuation difference (THAD) and pneumobilia in improving TG diagnostic performance

Kato, H., Takada, T., Strasberg, S., Isaji, S., Sano, K., Yoshida, M., Itoi, T., Okamoto, K., Kiriyama, S., Yagi, S., Matsubara, T., Higuchi, R., Ohyama, T., Misawa, T., Mukai, S., Mori, Y., Asai, K., Mizuno, S., Abe, Y. & Suzuki, K. & 14 others, Homma, Y., Hata, J., Tsukiyama, K., Kumamoto, Y., Tsuyuguchi, T., Maruo, H., Asano, Y., Hori, S., Shibuya, M., Mayumi, T., Toyota, N., Umezawa, A., Gomi, H. & Horiguchi, A., 2024 1月, In: Journal of Hepato-Biliary-Pancreatic Sciences. 31, 1, p. 12-24 13 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Anatomic, isolated complete caudate lobectomy using an anterior transhepatic approach with glissonian pedicle approach and indocyanine green fluorescence guidance: a case report

Endo, Y., Abe, Y., Kitago, M., Hasegawa, Y., Hori, S., Tanaka, M., Nakano, Y., Shimazu, M. & Kitagawa, Y., 2024 8月 1, In: Journal of Surgical Case Reports. 2024, 8, rjae505.

研究成果: Article › 査読

Open Access

A Novel Approach to Orthotopic Hepatocyte Transplantation Engineered With Liver Hydrogel for Fibrotic Livers, Enhancing Cell–Cell Interaction and Angiogenesis

Udagawa, D., Nagata, S., Yagi, H., Nishi, K., Morisaku, T., Adachi, S., Nakano, Y., Tanaka, M., Hori, S., Hasegawa, Y., Abe, Y., Kitago, M. & Kitagawa, Y., 2024 1月 1, In: Cell Transplantation. 33

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

Association between Renal Sinus Fat and Cardiometabolic and Renin-Angiotensin System Parameters in Primary Aldosteronism

Mitsuno, R., Kaneko, K., Nakamura, T., Kojima, D., Mizutani, Y., Azegami, T., Yamaguchi, S., Yamada, Y., Jinzaki, M., Kinouchi, K., Yoshino, J. & Hayashi, K., 2024 1月 1, In: Journal of the Endocrine Society. 8, 1, bvad154.

研究成果: Article › 査読

Open Access

Association of polydoctoring and mortality among persons over 85 years with multimorbidity: a prospective cohort study in Japan

Ando, T., Sasaki, T., Abe, Y., Nishimoto, Y., Hirata, T., Tajima, T., Oguma, Y., Haruta, J. & Arai, Y., 2024, In: BJGP Open. 8, 3, BJGPO.2024.0016.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Associations of clinical context-specific ambiguity tolerance with burnout and work engagement among Japanese physicians: a nationwide cross-sectional study

Fujikawa, H., Aoki, T., Ando, T. & Haruta, J., 2024 12月, In: BMC Medical Education. 24, 1, 660.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Characteristics of the studies using realist evaluation to assess interventions that address psychosocial healthcare issues in older adults: a scoping review

Mitani, S., Ogawara, H., Haruta, J., Sakakibara, T. & Fukahori, H., 2024 8月 30, In: BMJ open. 14, 8, e078256.

研究成果: Article › 査読

Open Access

Clinical relevance of proteinuria selectivity index and fractional excretion of sodium in patients with nephrotic syndrome

Nakayama, T., Azegami, T., Yamaguchi, S., Hirano, K., Komatsu, M., Fujii, K., Futatsugi, K., Urai, H., Kawaguchi, T., Itoh, T., Yoshimoto, N., Hagiwara, A., Hishikawa, A., Matsuda, H., Ando, T., Yamaji, Y., Murakami, M., Hashiguchi, A., Kaneko, Y. & Yokoo, T. & 1 others, Hayashi, K., 2024 12月, In: Scientific reports. 14, 1, 23755.

研究成果: Article › 査読

Open Access

Combining hemodialysis with peritoneal dialysis improves cognitive function: a three-case report

Maruki, T., Nakayama, T., Morimoto, K., Uchiyama, K., Washida, N., Mitsuno, R., Tonomura, S., Hama, E. Y., Kusahana, E., Yoshimoto, N., Hishikawa, A., Hagiwara, A., Azegami, T., Yoshino, J., Monkawa, T., Yoshida, T., Yamaguchi, S. & Hayashi, K., 2024 12月, In: CEN case reports. 13, 6, p. 517-521 5 p.

研究成果: Article › 査読

Community-based medical education (CBME), community comprehensive care education, and interprofessional education (IPE) in Japan: An exploration of their implementation

Haruta, J., 2024, In: Medical Teacher. 46, sup1, p. S46-S52

研究成果: Article › 査読

2 被引用数 (Scopus)

Competencies related to generalism for Japanese medical undergraduates: Essential skills for comprehensive care

Fujikawa, H., Ando, T., Endo, A., Kaneko, M., Shikino, K., Nagamine, Y., Nakayama, T., Nishigori, H., Yamanashi, H. & Haruta, J., 2024, In: Medical Teacher. 46, sup1, p. S21-S30

研究成果: Article › 査読

5 被引用数 (Scopus)

Determinants of polydoctoring among multimorbid older adults; a cross-sectional study in an urban area of Japan

Ando, T., Sasaki, T., Abe, Y., Nishimoto, Y., Hirata, T., Haruta, J. & Arai, Y., 2024 11月, In: Journal of General and Family Medicine. 25, 6, p. 376-383 8 p.

研究成果: Article › 査読

Open Access

Development of a validated assessment tool for medical students using simulated patients: an 8-year panel survey

Haruta, J., Nakajima, R. & Monkawa, T., 2024 12月, In: BMC Medical Education. 24, 1, 399.

研究成果: Article › 査読

Open Access

Early Initiation of Icodextrin Reduces Peritoneal Dialysis-Associated Peritonitis Risk: A Retrospective Cohort Study

Mitsuno, R., Nakayama, T., Morimoto, K., Uchiyama, K., Washida, N., Kusahana, E., Hama, E. Y., Tonomura, S., Yoshimoto, N., Hishikawa, A., Hagiwara, A., Azegami, T., Yoshino, J., Monkawa, T., Yoshida, T., Yamaguchi, S. & Hayashi, K., 2024, (Accepted/In press) In: Blood Purification.

研究成果: Article › 査読

Efficacy and safety of neoadjuvant S-1-based chemoradiotherapy in resectable and borderline-resectable pancreatic cancer: a long-term follow-up study

Shimane, G., Kitago, M., Endo, Y., Aiura, K., Yagi, H., Abe, Y., Hasegawa, Y., Hori, S., Tanaka, M., Nakano, Y., Fukada, J., Masugi, Y. & Kitagawa, Y., 2024 12月, In: World Journal of Surgical Oncology. 22, 1, 336.

研究成果: Article › 査読

Open Access

Efficacy of sucrose and povidone–iodine mixtures in peritoneal dialysis catheter exit-site care

Nakayama, T., Morimoto, K., Uchiyama, K., Washida, N., Kusahana, E., Hama, E. Y., Mitsuno, R., Tonomura, S., Yoshimoto, N., Hishikawa, A., Hagiwara, A., Azegami, T., Yoshino, J., Monkawa, T., Yoshida, T., Yamaguchi, S. & Hayashi, K., 2024 12月, In: BMC Nephrology. 25, 1, 151.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Exploring factors associated with healthcare professionals’ subjective perceptions of complex issues in primary care in Japan: a self-administered survey study on confidence, satisfaction and burden levels

Haruta, J. & Goto, R., 2024 3月 25, In: BMJ open. 14, 3, e081328.

研究成果: Article › 査読

Open Access

False-positive Serum Antiglomerular Basement Membrane Antibody due to Bovine Serum Albumin-containing Surgical Adhesive: A Case Report

Yoshida, R., Azegami, T., Yamaguchi, S., Hagiwara, A., Hishikawa, A., Yoshimoto, N., Hashiguchi, A. & Hayashi, K., 2024 10月, In: Kidney Medicine. 6, 10, 100880.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Family physicians have greater ambiguity tolerance in the clinical context: A nationwide cross-sectional study

Fujikawa, H., Aoki, T., Ando, T. & Haruta, J., 2024, (Accepted/In press) In: Journal of General and Family Medicine.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Hemodialysis treatment of vancomycin-induced drug reaction with eosinophilia and systemic symptoms/drug-induced hypersensitivity syndrome in a patient undergoing peritoneal dialysis

Mitsuno, R., Nakayama, T., Uchiyama, K., Yoshimoto, N., Kusahana, E., Morimoto, K., Yoshino, J., Yoshida, T., Kanda, T., Yamaguchi, S. & Hayashi, K., 2024 10月, In: CEN case reports. 13, 5, p. 339-345 7 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Identifying the Trends of Urinary microRNAs within Extracellular Vesicles for Esophageal Cancer

Hisaoka, K., Matsuda, S., Minoura, K., Yamaguchi, H., Ichikawa, Y., Mizunuma, M., Kobayashi, R., Morimoto, Y., Takeuchi, M., Fukuda, K., Nakamura, R., Hori, S., Yamazaki, T., Sambe, T., Kawakubo, H. & Kitagawa, Y., 2024 5月, In: Cancers. 16, 9, 1698.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Interprofessional competency in clinical students: validating the Clinical student version of the Japanese Self-assessment Scale of Interprofessional Competency (C-JASSIC)

Haruta, J., Tomizaki, E., Horiguchi, T., Nakamura, T., Ishikawa, S. & Monkawa, T., 2024, In: Journal of Interprofessional Care. 38, 5, p. 875-882 8 p.

研究成果: Article › 査読

Laypeople's Perspective on Physician Work-Hour Restrictions in Japan: A Cross-Sectional Study

Fujikawa, H. & Haruta, J., 2024 1月 1, In: Journal of Patient Experience. 11

研究成果: Article › 査読

Open Access

Molecular diagnosis for detecting KRAS mutation in peritoneal washing fluid of pancreatic ductal adenocarcinoma

Shimane, G., Nakano, Y., Matsuda, S., Kitago, M., Masugi, Y., Nakamura, K., Nakamura, Y., Yagi, H., Abe, Y., Hasegawa, Y., Hori, S., Tanaka, M., Takemura, R., Nishihara, H. & Kitagawa, Y., 2024 12月, In: Scientific reports. 14, 1, 21732.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Multiple site inflammation and acute kidney injury in crush syndrome

Miyauchi, H., Okubo, K., Iida, K., Kawakami, H., Takayama, K., Hayashi, Y., Haruta, J., Sasaki, J., Hayashi, K. & Hirahashi, J., 2024, In: Frontiers in Pharmacology. 15, 1458997.

研究成果: Article › 査読

Open Access

Prognosis prediction of PDAC via detection of O-glycan altered extracellular vesicles in perioperative sera

Uemura, S., Kabe, Y., Kitago, M., Matsuda, S., Abe, Y., Hasegawa, Y., Hori, S., Tanaka, M., Nakano, Y., Sato, Y., Itonaga, M., Ono, M., Kawakami, T., Suematsu, M. & Kitagawa, Y., 2024 11月, In: Cancer science. 115, 11, p. 3718-3728 11 p.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Renal sinus fat is associated with intrarenal hemodynamic abnormalities independent of visceral fat in patients with chronic kidney disease

Kaneko, K., Mitsuno, R., Kojima, D., Azegami, T., Kosugi, S., Nakamura, T., Hashiguchi, A., Yamada, Y., Jinzaki, M., Yamaguchi, S., Itoh, H., Yoshino, J. & Hayashi, K., 2024 3月 1, In: Obesity Research and Clinical Practice. 18, 2, p. 118-123 6 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men

Yamaguchi, S., Irie, J., Mitsuishi, M., Uchino, Y., Nakaya, H., Takemura, R., Inagaki, E., Kosugi, S., Okano, H., Yasui, M., Tsubota, K., Hayashi, K., Yoshino, J. & Itoh, H., 2024, In: Endocrine journal. 71, 2, p. 153-169 17 p.

研究成果: Article › 査読

Open Access

5 被引用数 (Scopus)

The impact of core curriculum revisions on Japanese medical schools: Navigating curriculum evolution

Haruta, J., Urushibara-Miyachi, Y., Ito, S., Takamura, A., Nitta, Y., Moriya, R. & Yamawaki, M., 2024, In: Medical Teacher. 46, sup1, p. S67-S75

研究成果: Article › 査読

1 被引用数 (Scopus)

The proteinuria selectivity index value predicts the remission of IgA nephropathy: a retrospective cohort study

Mitsuno, R., Nakayama, T., Ito, W., Maruki, T., Nakamichi, R., Adachi, K., Yoshimoto, N., Hishikawa, A., Hagiwara, A., Yamaguchi, S., Monkawa, T., Yoshino, J., Hashiguchi, A., Azegami, T. & Hayashi, K., 2024, In: Renal Failure. 46, 2, 2423839.

研究成果: Article › 査読

Open Access

アレルギー領域における診療科・職種横断的リカレント教育の重要性：「出前授業による教育の機会創出事業」参加者データの分析

Masaki, K., Sakashita, M., Ogawa, Y., Inomata, T., Kainuma, K., Kan-O, K., Sato, S., Tamari, M., Nakajima, S., Morita, H., Kurashima, Y., Futamura, M., Takahashi, K., Haruta, J., Hyakutake, M., Monkawa, T., Ishizuka, T., Imoto, Y., Oyama, N. & Kanzaki, S. & 6 others, Kidoguchi, M., Fukushima, A., Fukunaga, K., Fujieda, S., Yasutomi, M. & Adachi, T., 2024, In: Japanese Journal of Allergology. 73, 4, p. 329-339 11 p.

研究成果: Article › 査読

2023

Adipocyte NMNAT1 expression is essential for nuclear NAD⁺ biosynthesis but dispensable for regulating thermogenesis and whole-body energy metabolism

Yamaguchi, S., Kojima, D., Iqbal, T., Kosugi, S., Franczyk, M. P., Qi, N., Sasaki, Y., Yaku, K., Kaneko, K., Kinouchi, K., Itoh, H., Hayashi, K., Nakagawa, T. & Yoshino, J., 2023 9月 24, In: Biochemical and Biophysical Research Communications. 674, p. 162-169 8 p.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Antineutrophil cytoplasmic antibody-associated vasculitis predominantly manifesting tubulointerstitial nephritis: A case report

Nishioka, K., Yamaguchi, S., Hashiguchi, A., Yoshimoto, N., Tajima, T., Yasuda, I., Uchiyama, K., Kaneko, K., Aso, M., Yoshino, J., Monkawa, T., Kanda, T., Hayashi, K. & Itoh, H., 2023 1月 1, In: SAGE Open Medical Case Reports. 11

研究成果: Article › 査読

Open Access

Association between experience of interprofessional care and self-medication among family caregivers: A cross-sectional study

Masumoto, S., Nakayama, G., Haruta, J. & Maeno, T., 2023 5月, In: Research in Social and Administrative Pharmacy. 19, 5, p. 773-777 5 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Association between family caregivers' primary care experience when they report as patients and their stress related to caregiving: A pilot cross-sectional study

Nakayama, G., Masumoto, S., Haruta, J. & Maeno, T., 2023 7月, In: Journal of General and Family Medicine. 24, 4, p. 231-239 9 p.

研究成果: Article › 査読

Open Access

Association Between Varicella-Zoster Virus Vaccination and Patient Experience in Elderly Japanese Outpatients: A Case-Control Study

Inaba, T., Haruta, J., Goto, R. & Maeno, T., 2023 1月 1, In: Journal of Primary Care and Community Health. 14

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Case report: Importance of early and continuous tocilizumab therapy in nephrotic syndrome associated with idiopathic multicentric Castleman disease: A case series

Kojima, D., Yamaguchi, S., Hashiguchi, A., Hayashi, K., Uchiyama, K., Yoshimoto, N., Adachi, K., Nakayama, T., Nishioka, K., Tajima, T., Morimoto, K., Yoshino, J., Yoshida, T., Monkawa, T., Kanda, T. & Itoh, H., 2023 1月 9, In: Frontiers in Medicine. 9, 1037032.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Clinical characteristics and predictive factors of postoperative intra-abdominal abscess after distal pancreatectomy

Nakano, Y., Endo, Y., Kitago, M., Nishiyama, R., Yagi, H., Abe, Y., Hasegawa, Y., Hori, S., Tanaka, M., Shimane, G., Soga, S., Egawa, T., Okuda, S. & Kitagawa, Y., 2023 12月, In: Langenbeck's Archives of Surgery. 408, 1, 170.

研究成果: Article › 査読

4 被引用数 (Scopus)

Clinical significance of serum urea-to-creatinine ratio in patients undergoing peritoneal dialysis

Tonomura, S., Uchiyama, K., Nakayama, T., Mitsuno, R., Kojima, D., Hama, E. Y., Nagasaka, T., Nishimura, E. S., Kusahana, E., Takahashi, R., Yoshimoto, N., Yamaguchi, S., Morimoto, K., Yoshida, T., Hayashi, K., Kanda, T., Washida, N. & Itoh, H., 2023 12月, In: Therapeutic Apheresis and Dialysis. 27, 6, p. 1103-1112 10 p.

研究成果: Article › 査読

Open Access