1,2-cis-α-Stereoselective Glycosylation Utilizing a Glycosyl-Acceptor-Derived Borinic Ester and Its Application to the Total Synthesis of Natural Glycosphingolipids

研究成果: Article査読

47 被引用数 (Scopus)

抄録

1,2-cis-α-Stereoselective glycosylations were conducted using a 1,2-anhydroglucose donor and mono-ol acceptors in the presence of a glycosyl-acceptor-derived borinic ester. Reactions proceeded smoothly under mild conditions to provide the corresponding α-glycosides with high stereoselectivity in moderate to high yields. In addition, the present method was applied successfully to the direct glycosylation of a protected ceramide acceptor and the total synthesis of natural glycosphingolipids (GSLs).

本文言語English
ページ(範囲)5030-5033
ページ数4
ジャーナルOrganic Letters
18
19
DOI
出版ステータスPublished - 2016 10月 7

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

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