TY - JOUR
T1 - A case of metastatic colon cancer effectively treated by XELOX and IRIS
AU - Nishizawa, Toshihiro
AU - Kinoshita, Satoshi
AU - Sakuno, Takashi
AU - Fujiyama, Yoichi
AU - Kikuchi, Miho
AU - Kaneko, Hiroshi
AU - Suzuki, Hidekazu
AU - Takahashi, Masahiko
PY - 2013/6
Y1 - 2013/6
N2 - The patient was a 78-year-old woman who suffered from right upper quadrant pain. She was diagnosed as colon cancer with hepatic metastasis. Initial chemotherapy using capecitabine plus oxaliplatin (XELOX)+bevacizumab achieved partial response. After 12 months, XELOX was discontinued due to Grade 3 hand-foot syndrome and peripheral neuropathy. Irinotecan plus oral S-1 (a combination of tegafur, 5-chloro-2, 4-dihydroxypyridine, and potassium oxonate) and (IRIS)+bevacizumab were continued as second-line therapy, and her status was maintained as stable disease. XELOX and IRIS regimens do not require catheter placement and long infusion process, providing a great advantage to patients.
AB - The patient was a 78-year-old woman who suffered from right upper quadrant pain. She was diagnosed as colon cancer with hepatic metastasis. Initial chemotherapy using capecitabine plus oxaliplatin (XELOX)+bevacizumab achieved partial response. After 12 months, XELOX was discontinued due to Grade 3 hand-foot syndrome and peripheral neuropathy. Irinotecan plus oral S-1 (a combination of tegafur, 5-chloro-2, 4-dihydroxypyridine, and potassium oxonate) and (IRIS)+bevacizumab were continued as second-line therapy, and her status was maintained as stable disease. XELOX and IRIS regimens do not require catheter placement and long infusion process, providing a great advantage to patients.
KW - Colon cancer
KW - IRIS
KW - XELOX
UR - http://www.scopus.com/inward/record.url?scp=84882794680&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84882794680&partnerID=8YFLogxK
M3 - Article
C2 - 23863664
AN - SCOPUS:84882794680
SN - 0385-0684
VL - 40
SP - 807
EP - 809
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
IS - 6
ER -
