TY - JOUR
T1 - A case of persistent elevation of serum glutamic oxaloacetic transaminase due to enzyme-immunoglobulin complex formation
AU - Kato, Shinzo
AU - Ishii, Hiromasa
AU - Takagi, Toshikazu
AU - Asaba, Yoshiaki
AU - Ichijo, Makoto
AU - Tsuchiya, Masaharu
AU - Kano, Shojiro
AU - Saga, Mieko
AU - Horii, Kouji
PY - 1983/1
Y1 - 1983/1
N2 - A 43 year-old male, who has no complaints, was admitted for the evaluation of the persistent elevation of serum Glutamic Oxaloacetic Transaminase (GOT) activity. He showed slight hepatomegaly, but no other abnormal findings in physical examination. The abnormal laboratory finding was found only in serum GOT level, and other tests including ECG, EMG, ICG-15 min, liver scintigram and histology of biopsied liver were normal. By using electrophoresis and immunofixation technique, we found that serum GOT was bound to immunoglobulin IgG (A) and formed enzyme-immunogolbulin complex. Elevation of serum GOT seemed to be derived from the delayed disappearance rate of GOT from the blood, and not from the increase in release of GOT from the tissues.
AB - A 43 year-old male, who has no complaints, was admitted for the evaluation of the persistent elevation of serum Glutamic Oxaloacetic Transaminase (GOT) activity. He showed slight hepatomegaly, but no other abnormal findings in physical examination. The abnormal laboratory finding was found only in serum GOT level, and other tests including ECG, EMG, ICG-15 min, liver scintigram and histology of biopsied liver were normal. By using electrophoresis and immunofixation technique, we found that serum GOT was bound to immunoglobulin IgG (A) and formed enzyme-immunogolbulin complex. Elevation of serum GOT seemed to be derived from the delayed disappearance rate of GOT from the blood, and not from the increase in release of GOT from the tissues.
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U2 - 10.2957/kanzo.24.664
DO - 10.2957/kanzo.24.664
M3 - Article
AN - SCOPUS:84913041140
SN - 0451-4203
VL - 24
SP - 664
EP - 668
JO - Acta Hepatologica Japonica
JF - Acta Hepatologica Japonica
IS - 6
ER -