A 43 year-old male, who has no complaints, was admitted for the evaluation of the persistent elevation of serum Glutamic Oxaloacetic Transaminase (GOT) activity. He showed slight hepatomegaly, but no other abnormal findings in physical examination. The abnormal laboratory finding was found only in serum GOT level, and other tests including ECG, EMG, ICG-15 min, liver scintigram and histology of biopsied liver were normal. By using electrophoresis and immunofixation technique, we found that serum GOT was bound to immunoglobulin IgG (A) and formed enzyme-immunogolbulin complex. Elevation of serum GOT seemed to be derived from the delayed disappearance rate of GOT from the blood, and not from the increase in release of GOT from the tissues.
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