TY - GEN
T1 - A hybrid MC-FEM model for analysis of light propagation in highly scattering medium
AU - Kurihara, Kazuki
AU - Wu, Xue
AU - Okada, Eiji
AU - Dehghani, Hamid
PY - 2013/8/12
Y1 - 2013/8/12
N2 - The hemodynamic change related to the brain activation can be located by the diffuse optical tomography (DOT) using the near-infrared spectroscopy (NIRS) signals and the spatial sensitivity profiles (SSP). Monte Carlo (MC) method and finite element method (FEM) have been used to predict the SSPs. The computation time for MC method is much longer than that for the FEM, however, the accurate solution in the region close to the light source cannot be obtained by FEM solutions of the diffusion equation. In this study, a hybrid MC-FEM model is proposed for fast and accurate simulation of light propagation in a highly scattering medium. In the hybrid model, the solution in the region close to the light source is calculated by the MC method whereas that in the region far from the light source is calculated by the FEM. The solutions by the FEM in hemispherical models were compared with thoseby the MC method to determine the region in which diffusion approximation does not hold and the number of photons for the MC method for the hybrid model. The results demonstratethat theproposed hybrid model can calculatethe accurate solutionswithin reasonable computation time for a multi-layered model.
AB - The hemodynamic change related to the brain activation can be located by the diffuse optical tomography (DOT) using the near-infrared spectroscopy (NIRS) signals and the spatial sensitivity profiles (SSP). Monte Carlo (MC) method and finite element method (FEM) have been used to predict the SSPs. The computation time for MC method is much longer than that for the FEM, however, the accurate solution in the region close to the light source cannot be obtained by FEM solutions of the diffusion equation. In this study, a hybrid MC-FEM model is proposed for fast and accurate simulation of light propagation in a highly scattering medium. In the hybrid model, the solution in the region close to the light source is calculated by the MC method whereas that in the region far from the light source is calculated by the FEM. The solutions by the FEM in hemispherical models were compared with thoseby the MC method to determine the region in which diffusion approximation does not hold and the number of photons for the MC method for the hybrid model. The results demonstratethat theproposed hybrid model can calculatethe accurate solutionswithin reasonable computation time for a multi-layered model.
KW - Analysis of light propagation
KW - Diffuse optical imaging
KW - Finite element method
KW - Monte Carlo method
UR - http://www.scopus.com/inward/record.url?scp=84881189771&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84881189771&partnerID=8YFLogxK
U2 - 10.1117/12.2032613
DO - 10.1117/12.2032613
M3 - Conference contribution
AN - SCOPUS:84881189771
SN - 9780819496485
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Diffuse Optical Imaging IV
T2 - Diffuse Optical Imaging IV
Y2 - 12 May 2013 through 14 May 2013
ER -