TY - JOUR
T1 - A method of tagging the nuclear fragmentation event induced by 11C for cancer therapy
AU - Maruyama, Koichi
AU - Hanada, Takashi
AU - Kikumura, Riki
AU - Kanazawa, Mitsutaka
AU - Suda, Toshimi
AU - Maeda, Kazushige
N1 - Funding Information:
Manuscript received November 15, 2004. This work was supported in part by the project research program (2002–2004) of the Graduate School of Medical Science, Kitasato University, in part by the special research program of the AHS, Kitasato University, Japan, and in part by the HIMAC, NIRS, Japan. K. Maruyama is with the School of Allied Health Sciences, Kitasato University, Kanagawa 228-8555, Japan and CREST, JST, Saitama 332–0012, Japan (e-mail: [email protected]). T. Hanadaand R. Kikumura are with the National Hospital Organization Tokyo Medical Center, Tokyo 152–8902, Japan. K. Kanazawa is with the National Institute of Radiological Sciences, Chiba, Chiba 263–8555, Japan. T. Suda is with the Institute of Physical and Chemical Research (RIKEN), Saitama 351–0198, Japan. K. Maeda is with the Graduate School of Science, Tohoku University, Miyagi 980–8578, Japan. Digital Object Identifier 10.1109/TNS.2006.869839
PY - 2006/2
Y1 - 2006/2
N2 - Heavy ion cancer therapy using energetic 12C ions has been carried out successfully at the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. The method has advantages over traditional radiation therapy using an energetic photon beam in two respects: the dose concentration owing to the Bragg peak and high biological effects. The development of a cancer therapy using 11C ions is also currently underway at HIMAC, however, there remains the problem of beam attenuation due to nuclear fragmentation reactions in the body of the patient; this requires modification of the dose calculation for the therapy. To the best of our knowledge, no research on 11C-induced nuclear fragmentation reactions has yet been published. We propose a method of identifying the nuclear fragmentation reaction event induced by the carbon beams using a total-absorption-type target detector, that plays the role of a human phantom, and a system of plastic scintillation counters surrounding the phantom. We have carried out measurements for the carbon beams with the detector system. A portion of the beam energy is lost as escaping fragment particles from the phantom, leading to a decrease in beam intensity. We were able to successfully detect nuclear reaction events on an event-by-event basis.
AB - Heavy ion cancer therapy using energetic 12C ions has been carried out successfully at the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. The method has advantages over traditional radiation therapy using an energetic photon beam in two respects: the dose concentration owing to the Bragg peak and high biological effects. The development of a cancer therapy using 11C ions is also currently underway at HIMAC, however, there remains the problem of beam attenuation due to nuclear fragmentation reactions in the body of the patient; this requires modification of the dose calculation for the therapy. To the best of our knowledge, no research on 11C-induced nuclear fragmentation reactions has yet been published. We propose a method of identifying the nuclear fragmentation reaction event induced by the carbon beams using a total-absorption-type target detector, that plays the role of a human phantom, and a system of plastic scintillation counters surrounding the phantom. We have carried out measurements for the carbon beams with the detector system. A portion of the beam energy is lost as escaping fragment particles from the phantom, leading to a decrease in beam intensity. We were able to successfully detect nuclear reaction events on an event-by-event basis.
KW - Cancer
KW - Ion beams
KW - Medical treatment
KW - Nuclear fragmentation reaction
KW - Nuclear measurement
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U2 - 10.1109/TNS.2006.869839
DO - 10.1109/TNS.2006.869839
M3 - Article
AN - SCOPUS:33645679492
SN - 0018-9499
VL - 53
SP - 346
EP - 350
JO - IEEE Transactions on Nuclear Science
JF - IEEE Transactions on Nuclear Science
IS - 1
ER -