A microfluidic organoid trapping device to form tube-like intestinal organoids

Miki Matsumoto, Yuya Morimoto, Toshiro Sato, Shoji Takeuchi

研究成果: Conference contribution

抄録

We propose an organoid-trapping device to form long intestinal epithelial organoids. The device is drivable with hydrostatic pressure to gather standard organoids, and induces their fusion in the microchannel. We can control the length of the tube-like organoids by adjusting the number of standard organoids. As a demonstration, six organoids were trapped in the device and tube-like organoids were formed by their fusion within two days. Our device will provide desired length of organoids for development of a perfusable 3D intestinal organoid model.

本文言語English
ホスト出版物のタイトルMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Chemical and Biological Microsystems Society
ページ871-872
ページ数2
ISBN(電子版)9781733419017
出版ステータスPublished - 2020
イベント24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
継続期間: 2020 10月 42020 10月 9

出版物シリーズ

名前MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
CityVirtual, Online
Period20/10/420/10/9

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング
  • 化学一般
  • 制御およびシステム工学

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