@article{a886dad648174d6987cca22313d17952,
title = "A new NF-κB inhibitor based on the amino-epoxyquinol core of DHMEQ",
abstract = "The amino-epoxyquinols 6a and 6b were synthesized as soluble derivatives of an NF-κB inhibitor DHMEQ (1). In spite of the opposite configuration from 1, 6b rather than 6a affected the deactivation of NF-κB, based on NO secretion and MALDI-TOF MS analysis. It was indicated that 6b inhibited the activation by different manner from that of 1.",
keywords = "DHMEQ, Epoxyquinol derivatives, NF-κB inhibitor",
author = "Tsuyoshi Saitoh and Chika Shimada and Masatoshi Takeiri and Mitsuhiro Shiino and Shigeru Ohba and Rika Obata and Yuichi Ishikawa and Kazuo Umezawa and Shigeru Nishiyama",
note = "Funding Information: This work was supported by the High-Tech Research Center Project for Private Universities Matching Fund (2006–2011) from MEXT, The Science Research Promotion Fund from The Promotion and Mutual Aid Corporation for Private Schools of Japan, and the program Promotion of Fundamental Studies in Health Sciences of the National Institute of Biomedical Innovation (NIBIO), 2006–2011. T.S. was indebted to Global COE Program {\textquoteleft}Center for Human Metabolomic Systems Biology{\textquoteright} from MEXT.",
year = "2010",
month = oct,
day = "1",
doi = "10.1016/j.bmcl.2010.08.036",
language = "English",
volume = "20",
pages = "5638--5642",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Limited",
number = "19",
}