A novel cyclic lipoundecapeptide, pholipeptin, isolated from Pseudomonas sp.

Hideaki Ui; Toshiaki Miyake; Hironobu Iinuma; Masaya Imoto; Seiko Hattori; Masa Hamada; Tomio Takeuchi; Sumio Umezawa; Kazuo Umezawa

doi:10.1016/0040-4039(95)01601-5

A novel cyclic lipoundecapeptide, pholipeptin, isolated from Pseudomonas sp.

Hideaki Ui, Toshiaki Miyake, Hironobu Iinuma, Masaya Imoto, Seiko Hattori, Masa Hamada, Tomio Takeuchi, Sumio Umezawa, Kazuo Umezawa

生命情報学科

研究成果: Article › 査読

7 被引用数 (Scopus)

抄録

An inhibitor of phosphatidylinositol-specific phospholipase C, pholipeptin, was purified from the culture broth of Pseudomonas sp. Structural determination by 2D NMR spectroscopy with addition of a small amount of trifluoroacetic acid revealed that it was a novel cyclic lipodepsipeptide (1) consisting of 11 amino acids and a 3-hydroxydecanoic acid moiety.

本文言語	English
ページ（範囲）	7479-7480
ページ数	2
ジャーナル	Tetrahedron Letters
巻	36
号	41
DOI	https://doi.org/10.1016/0040-4039(95)01601-5
出版ステータス	Published - 1995 10月 9

ASJC Scopus subject areas

生化学
創薬
有機化学

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10.1016/0040-4039(95)01601-5

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title = "A novel cyclic lipoundecapeptide, pholipeptin, isolated from Pseudomonas sp.",

abstract = "An inhibitor of phosphatidylinositol-specific phospholipase C, pholipeptin, was purified from the culture broth of Pseudomonas sp. Structural determination by 2D NMR spectroscopy with addition of a small amount of trifluoroacetic acid revealed that it was a novel cyclic lipodepsipeptide (1) consisting of 11 amino acids and a 3-hydroxydecanoic acid moiety.",

author = "Hideaki Ui and Toshiaki Miyake and Hironobu Iinuma and Masaya Imoto and Seiko Hattori and Masa Hamada and Tomio Takeuchi and Sumio Umezawa and Kazuo Umezawa",

year = "1995",

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language = "English",

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T1 - A novel cyclic lipoundecapeptide, pholipeptin, isolated from Pseudomonas sp.

AU - Ui, Hideaki

AU - Miyake, Toshiaki

AU - Iinuma, Hironobu

AU - Imoto, Masaya

AU - Hattori, Seiko

AU - Hamada, Masa

AU - Takeuchi, Tomio

AU - Umezawa, Sumio

AU - Umezawa, Kazuo

PY - 1995/10/9

Y1 - 1995/10/9

N2 - An inhibitor of phosphatidylinositol-specific phospholipase C, pholipeptin, was purified from the culture broth of Pseudomonas sp. Structural determination by 2D NMR spectroscopy with addition of a small amount of trifluoroacetic acid revealed that it was a novel cyclic lipodepsipeptide (1) consisting of 11 amino acids and a 3-hydroxydecanoic acid moiety.

AB - An inhibitor of phosphatidylinositol-specific phospholipase C, pholipeptin, was purified from the culture broth of Pseudomonas sp. Structural determination by 2D NMR spectroscopy with addition of a small amount of trifluoroacetic acid revealed that it was a novel cyclic lipodepsipeptide (1) consisting of 11 amino acids and a 3-hydroxydecanoic acid moiety.

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U2 - 10.1016/0040-4039(95)01601-5

DO - 10.1016/0040-4039(95)01601-5

M3 - Article

AN - SCOPUS:0029135391

SN - 0040-4039

VL - 36

SP - 7479

EP - 7480

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 41

ER -

A novel cyclic lipoundecapeptide, pholipeptin, isolated from Pseudomonas sp.

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